CABT-BL8384

antibody from Creative Diagnostics

Targeting: TNFRSF1A CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60

Functional assay (Recommended by provider)

Antibody Data

Product number

CABT-BL8384

Provider

Creative Diagnostics

Product name

Anti-TNFRSF1A Monoclonal antibody, clone 66S-280

Antibody type

Monoclonal

Description

Tumor necrosis factor receptor 1 (TNFR1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors. This receptor plays an important role in mediating apoptosis. TNFR1 also plays an important role in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression. The extracellular domain of the receptor is also released into the circulatory system as soluble TNFR1 (sTNFR1). In humans, the TNFR1 gene is located on chromosome 12.

Reactivity

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

66S-280

Vial size

50 ug