BMS1013

antibody from Invitrogen Antibodies

Targeting: TNFRSF1A CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60

ELISA (Recommended by provider)

Antibody Data

Product number

BMS1013

Provider

Invitrogen Antibodies

Product name

CD120a (TNF Receptor I) Monoclonal Antibody (TBP-1), eBioscience™

Antibody type

Monoclonal

Antigen

Other

Description

Description: The monoclonal antibody TBP-1 recognizes Tumor Necrosis Factor Receptor type I (TNF-RI) TNF-receptors have been demonstrated on a wide variety of human somatic cells including fibroblasts, endothelial cells, adipocytes, liver membranes, granulocytes and several tumor cell lines. Based on gel filtration experiments the receptor appears to be a complex of different proteins with a molecular weight of 350 kDa. In a variety of cell lines two different types of TNF receptors with 75-80 and 55-60 kDa respectively have been identified. The cDNAs encoding the two different TNF receptors have been cloned. The exact mechanism of signal transduction after binding of TNF to the receptor is still unclear. The extracellular fragment of the 60 kDa TNF receptor, with a molecular mass of about 30 kDa was purified, partially sequenced, and the respective cDNA was cloned. This TNF binding protein is liberated from the intact molecule by proteolytic cleavage and comprises most of the extracellular portion of the receptor, including all three N-glycosylation sites. Applications Tested: ELISA.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

TBP-1

Vial size

100 µg

Concentration

1 mg/mL

Storage

-20°C