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Learn60192-1-Ig
antibody from Proteintech Group
Targeting: TNFRSF1A
CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60
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- Antibody Data
- Antigen structure
- References [21]
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- Validations
- Western blot [1]
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- Product number
- 60192-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60192-1-Ig, RRID:AB_10897160
- Product name
- TNFR1 antibody
- Antibody type
- Monoclonal
- Description
- TNFR1 antibody (Cat. #60192-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2A6E3
- Vial size
- 20ul, 150ul
Submitted references Targeting the DSTYK-ULK1 axis rewires TNFR1 signaling to overcome treatment resistance in lung cancer.
Nanoparticles coated with osteoblast-like cell membranes as curcumin delivery vehicles for targeted postmenopausal osteoporosis therapy.
Yixinyuan Gaofang ameliorates myocardial infarction in rats by inhibiting the TNF/NF-κB pathway.
Cigarette Smoking Induces Skeletal Muscle Atrophy in Mice by Activated Macrophage-Mediated Pyroptosis.
Sclareol can effectively ameliorate Feline calicivirus induced lung injury via the inhibition of inflammation and apoptosis.
Kaempferol attenuates experimental autoimmune neuritis through TNFR1/JNK/p38 signaling pathway inhibition.
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33.
Hydrogen protects against autoimmune myocarditis by inhibiting necroptosis via the TNF/TNFR1 signalling pathway.
Neural representation of cytokines by vagal sensory neurons.
Single-cell RNA-sequencing analysis reveals α-syn induced astrocyte-neuron crosstalk-mediated neurotoxicity.
High temperature ameliorates high-fat diet-induced obesity by promoting ceramide breakdown in skeletal muscle tissue.
Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis.
Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X(3)R Signaling Pathway in SD Rats.
EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice.
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
An experimental model of the epithelial to mesenchymal transition and pro-fibrogenesis in urothelial cells related to bladder pain syndrome/interstitial cystitis.
Progranulin Promotes Regeneration of Inflammatory Periodontal Bone Defect in Rats via Anti-inflammation, Osteoclastogenic Inhibition, and Osteogenic Promotion.
Inflammatory factor TNF-α promotes the growth of breast cancer via the positive feedback loop of TNFR1/NF-κB (and/or p38)/p-STAT3/HBXIP/TNFR1.
Pasquier A, Viu-Idocin C, Arricibita A, Echepare M, Picabea B, Orive D, Álava A, Fernández-Irigoyen J, Santamaría E, Argueta A, Molina E, Pineda-Lucena A, Gentili M, Facchinetti F, Roz L, Montuenga LM, Valencia K
Cell reports 2026 Mar 24;45(3):117087
Cell reports 2026 Mar 24;45(3):117087
Nanoparticles coated with osteoblast-like cell membranes as curcumin delivery vehicles for targeted postmenopausal osteoporosis therapy.
Li Q, Liu S, Sun T, Liu K, Li P, Zhu Y, Kou Y
Materials today. Bio 2026 Feb;36:102636
Materials today. Bio 2026 Feb;36:102636
Yixinyuan Gaofang ameliorates myocardial infarction in rats by inhibiting the TNF/NF-κB pathway.
Xiao L, Xiao B, Xiao J, Li Y, Zou Z, Liu Y, Peng T, He J
Scientific reports 2026 Apr 11;
Scientific reports 2026 Apr 11;
Cigarette Smoking Induces Skeletal Muscle Atrophy in Mice by Activated Macrophage-Mediated Pyroptosis.
Tan Y, Ye Y, Huang C, Li J, Huang L, Wei X, Liang T, Qin E, Xiong G, Bin Y
Journal of inflammation research 2025;18:2447-2464
Journal of inflammation research 2025;18:2447-2464
Sclareol can effectively ameliorate Feline calicivirus induced lung injury via the inhibition of inflammation and apoptosis.
Yan Y, Yang M, Liu Z, Li L, Fu Z, Jiao Y, Li M, Li Y, Yao H, Shen Z, Peng G
International immunopharmacology 2025 Oct 30;164:115342
International immunopharmacology 2025 Oct 30;164:115342
Kaempferol attenuates experimental autoimmune neuritis through TNFR1/JNK/p38 signaling pathway inhibition.
Wang L, Gu T, Yu C, Gao Y, Xuan T, Shen K, Wang G, Wang Z
International immunopharmacology 2025 Feb 6;147:113951
International immunopharmacology 2025 Feb 6;147:113951
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33.
Li J, Wu Z, Li N, Wang J, Huang M, Zhu L, Wan G, Zhang Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 19;74(1):42
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 19;74(1):42
Hydrogen protects against autoimmune myocarditis by inhibiting necroptosis via the TNF/TNFR1 signalling pathway.
Pan S, Yu M, Fan B, Wang B, Yang X, Zhang J, Liu X, Hong X, Yang W
Clinical immunology (Orlando, Fla.) 2025 Aug 12;:110577
Clinical immunology (Orlando, Fla.) 2025 Aug 12;:110577
Neural representation of cytokines by vagal sensory neurons.
Huerta TS, Chen AC, Chaudhry S, Tynan A, Morgan T, Park K, Adamovich-Zeitlin R, Haider B, Li JH, Nagpal M, Zanos S, Pavlov VA, Brines M, Zanos TP, Chavan SS, Tracey KJ, Chang EH
Nature communications 2025 Apr 24;16(1):3840
Nature communications 2025 Apr 24;16(1):3840
Single-cell RNA-sequencing analysis reveals α-syn induced astrocyte-neuron crosstalk-mediated neurotoxicity.
Li K, Ling H, Huang W, Luo W, Gu C, Tao B, Xie Q, Qiu P
International immunopharmacology 2024 Sep 30;139:112676
International immunopharmacology 2024 Sep 30;139:112676
High temperature ameliorates high-fat diet-induced obesity by promoting ceramide breakdown in skeletal muscle tissue.
Wang Q, Chen L, Zhang J, Liu Y, Jin Y, Wu J, Ren Z
Life metabolism 2024 Oct;3(5):loae012
Life metabolism 2024 Oct;3(5):loae012
Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis.
Xiao B, Jiang Y, Yuan S, Cai L, Xu T, Jia L
MedComm 2024 Jan;5(1):e457
MedComm 2024 Jan;5(1):e457
Electroacupuncture Alleviates Dry Eye Ocular Pain Through TNF-ɑ Mediated ERK1/2/P2X(3)R Signaling Pathway in SD Rats.
Wan MM, Jin T, Fu ZY, Lai SH, Gao WP
Journal of pain research 2023;16:4241-4252
Journal of pain research 2023;16:4241-4252
EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.
Zhang H, Zhang X, Ling C, Liu C, Hua S, Xiong Z, Zhao H, Feng Q, Feng Z, Tang J, Hong X
International immunopharmacology 2023 Apr;117:109902
International immunopharmacology 2023 Apr;117:109902
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Zhang M, Wu L, Deng Y, Peng F, Wang T, Zhao Y, Chen P, Liu J, Cai G, Wang L, Wu J, Chen X
Frontiers in immunology 2022;13:857025
Frontiers in immunology 2022;13:857025
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Zhao Y, Zhang T, Shen X, Huang A, Li H, Wang L, Liu X, Wang X, Song X, Wang S, Dong J, Shao N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice.
Wang Q, Liu Y, Xu Y, Jin Y, Wu J, Ren Z
Life sciences 2022 Jun 15;299:120540
Life sciences 2022 Jun 15;299:120540
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587.
Lin K, Shen SH, Lu F, Zheng P, Wu S, Liao J, Jiang X, Zeng G, Wei D
Journal of translational medicine 2022 Feb 19;20(1):96
Journal of translational medicine 2022 Feb 19;20(1):96
An experimental model of the epithelial to mesenchymal transition and pro-fibrogenesis in urothelial cells related to bladder pain syndrome/interstitial cystitis.
Jin XW, Wang QZ, Zhao Y, Liu BK, Zhang X, Wang XJ, Lu GL, Pan JW, Shao Y
Translational andrology and urology 2021 Nov;10(11):4120-4131
Translational andrology and urology 2021 Nov;10(11):4120-4131
Progranulin Promotes Regeneration of Inflammatory Periodontal Bone Defect in Rats via Anti-inflammation, Osteoclastogenic Inhibition, and Osteogenic Promotion.
Chen Q, Cai J, Li X, Song A, Guo H, Sun Q, Yang C, Yang P
Inflammation 2019 Feb;42(1):221-234
Inflammation 2019 Feb;42(1):221-234
Inflammatory factor TNF-α promotes the growth of breast cancer via the positive feedback loop of TNFR1/NF-κB (and/or p38)/p-STAT3/HBXIP/TNFR1.
Cai X, Cao C, Li J, Chen F, Zhang S, Liu B, Zhang W, Zhang X, Ye L
Oncotarget 2017 Aug 29;8(35):58338-58352
Oncotarget 2017 Aug 29;8(35):58338-58352
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TNFR1 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human TNFR1. This antibody recognizes human,mouse antigen. The TNFR1 antibody has been validated for the following applications: ELISA, WB analysis.
