3661

antibody from Cell Signaling Technology, Inc

Targeting: ACACB ACC2, ACCB, HACC275

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

3661

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#3661, RRID:AB_330337

Product name

Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

Critical role for free radicals on sprint exercise-induced CaMKII and AMPKα phosphorylation in human skeletal muscle.

Morales-Alamo D, Ponce-González JG, Guadalupe-Grau A, Rodríguez-García L, Santana A, Cusso R, Guerrero M, Dorado C, Guerra B, Calbet JA
Journal of applied physiology (Bethesda, Md. : 1985) 2013 Mar 1;114(5):566-77

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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.

Fullerton MD, Galic S, Marcinko K, Sikkema S, Pulinilkunnil T, Chen ZP, O'Neill HM, Ford RJ, Palanivel R, O'Brien M, Hardie DG, Macaulay SL, Schertzer JD, Dyck JR, van Denderen BJ, Kemp BE, Steinberg GR
Nature medicine 2013 Dec;19(12):1649-54

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Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPKα phosphorylation, in response to sprint exercise in severe acute hypoxia in humans.

Morales-Alamo D, Ponce-González JG, Guadalupe-Grau A, Rodríguez-García L, Santana A, Cusso MR, Guerrero M, Guerra B, Dorado C, Calbet JA
Journal of applied physiology (Bethesda, Md. : 1985) 2012 Sep;113(6):917-28

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Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ
Cell 2011 May 13;145(4):607-21

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Hyaluronan synthesis is inhibited by adenosine monophosphate-activated protein kinase through the regulation of HAS2 activity in human aortic smooth muscle cells.

Vigetti D, Clerici M, Deleonibus S, Karousou E, Viola M, Moretto P, Heldin P, Hascall VC, De Luca G, Passi A
The Journal of biological chemistry 2011 Mar 11;286(10):7917-24

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Novel nucleolar pathway connecting intracellular energy status with p53 activation.

Kumazawa T, Nishimura K, Kuroda T, Ono W, Yamaguchi C, Katagiri N, Tsuchiya M, Masumoto H, Nakajima Y, Murayama A, Kimura K, Yanagisawa J
The Journal of biological chemistry 2011 Jun 10;286(23):20861-9

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Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

Göransson O, McBride A, Hawley SA, Ross FA, Shpiro N, Foretz M, Viollet B, Hardie DG, Sakamoto K
The Journal of biological chemistry 2007 Nov 9;282(45):32549-60

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Extracellular adenosine activates AMP-dependent protein kinase (AMPK).

Aymerich I, Foufelle F, Ferré P, Casado FJ, Pastor-Anglada M
Journal of cell science 2006 Apr 15;119(Pt 8):1612-21

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Metabolic adaptations to fasting and chronic caloric restriction in heart, muscle, and liver do not include changes in AMPK activity.

Gonzalez AA, Kumar R, Mulligan JD, Davis AJ, Weindruch R, Saupe KW
American journal of physiology. Endocrinology and metabolism 2004 Nov;287(5):E1032-7

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Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: a new mechanism of action of insulin-sensitizing drugs.

Pilon G, Dallaire P, Marette A
The Journal of biological chemistry 2004 May 14;279(20):20767-74

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.

Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA, Cantley LC
Proceedings of the National Academy of Sciences of the United States of America 2004 Mar 9;101(10):3329-35