ALX4

gene product
FPP, KIAA1788, PFM, PFM2
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
288 antibodies from 21 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
73 antibodies
OriGene
60 antibodies
Invitrogen Antibodies
7 antibodies
LifeSpan BioSciences, Inc.
56 antibodies
Novus Biologicals
31 antibodies
Acris Antibodies GmbH
2 antibodies
Biorbyt
9 antibodies
Abgent
2 antibodies
St John's Laboratory
1 antibody
Aviva Systems Biology
7 antibodies
GeneTex
5 antibodies
ProSci
5 antibodies
Atlas Antibodies
1 antibody
MyBioSource
4 antibodies
Boster Biological Technology
1 antibody
United States Biological
13 antibodies
Creative Diagnostics
2 antibodies
GenWay
3 antibodies
Creative Biolabs
1 antibody
Sigma-Aldrich
3 antibodies
Abnova Corporation
2 antibodies