HPA027024

antibody from Atlas Antibodies

Targeting: EYA2 EAB1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA027024

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA027024, RRID:AB_1848334

Product name

Anti-EYA2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human EYA2, Gene description: EYA transcriptional coactivator and phosphatase 2, Alternative Gene Names: EAB1, Validated applications: IHC, WB, Uniprot ID: O00167, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe

Zhang G, Dong Z, Gimple R, Wolin A, Wu Q, Qiu Z, Wood L, Shen J, Jiang L, Zhao L, Lv D, Prager B, Kim L, Wang X, Zhang L, Anderson R, Moore J, Bao S, Keller T, Lin G, Kang C, Hamerlik P, Zhao R, Ford H, Rich J
Journal of Experimental Medicine 2021;218(11)

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Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis

Zhou H, Blevins M, Hsu J, Kong D, Galbraith M, Goodspeed A, Culp-Hill R, Oliphant M, Ramirez D, Zhang L, Trinidad-Pineiro J, Mathews Griner L, King R, Barnaeva E, Hu X, Southall N, Ferrer M, Gustafson D, Regan D, D'Alessandro A, Costello J, Patnaik S, Marugan J, Zhao R, Ford H
Cancer Research 2020;80(12):2689-2702

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Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells

Anantharajan J, Zhou H, Zhang L, Hotz T, Vincent M, Blevins M, Jansson A, Kuan J, Ng E, Yeo Y, Baburajendran N, Lin G, Hung A, Joy J, Patnaik S, Marugan J, Rudra P, Ghosh D, Hill J, Keller T, Zhao R, Ford H, Kang C
Molecular Cancer Therapeutics 2019;18(9):1484-1496

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Eyes absent homologue 2 predicts a favorable prognosis in colorectal cancer

Zheng J, Cao F, Huang X, Ramen K, Xu X, Zhu Y, Chang W, Shan Y, Guo A
OncoTargets and Therapy 2018;Volume 11

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A phosphotyrosine switch determines the antitumor activity of ERβ

Yuan B, Cheng L, Chiang H, Xu X, Han Y, Su H, Wang L, Zhang B, Lin J, Li X, Xie X, Wang T, Tekmal R, Curiel T, Yuan Z, Elledge R, Hu Y, Ye Q, Li R
Journal of Clinical Investigation 2014;124(8):3378-3390

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Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial–mesenchymal transition, and cancer stem cell properties

Farabaugh S, Micalizzi D, Jedlicka P, Zhao R, Ford H
Oncogene 2011;31(5):552-562