Antibody data
- Antibody Data
- Antigen structure
- References [33]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10308-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10308-1-AP, RRID:AB_513239
- Product name
- AMPK Beta 1 antibody
- Antibody type
- Polyclonal
- Description
- AMPK Beta 1 antibody (Cat. #10308-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Flavonoid-rich extracts of Nelumbo nucifera leaves alleviate obesity in HFD-fed mice via microbiota-dependent modulation of brown fat thermogenesis.
Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer.
Enhanced bioactivity of honeysuckle-Cassia seeds extracts through Lactobacillus acidophilus and Bacillus subtilis co-fermentation: Impact on alcoholic liver disease and gut microbiota.
Ganoderic acid a derivative induces apoptosis of cervical cancer cells by inhibiting JNK pathway.
CANDiT: A machine learning framework for differentiation therapy in colorectal cancer.
Hypoglycemic effect of dietary fibers from Moringa oleifera leaves: In vitro and in vivo studies.
Salidroside alleviates doxorubicin-induced hepatotoxicity via Sestrin2/AMPK-mediated pyroptotic inhibition.
Xiasangju alleviates hepatic insulin resistance in db/db mice via AMPK pathway: Mechanisms and active components study.
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway.
Hawthorn total flavonoids ameliorate hyperlipidemia through AMPK/SREBP1-c and PPARα/PGC-1α/CPT-1A pathway activation and gut microbiota modulation.
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.
Shionone Inhibits Glomerular Fibirosis by Suppressing NLRP3 Related Inflammasome though SESN2-NRF2/ HO-1 Pathway.
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
SGLT2i continuously prevents cardiac hypertrophy by reducing ferroptosis via AMPK up-regulation.
IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPKα to attenuate hypercholesterolemia.
LAPTM5 confers cisplatin resistance in NSCLC by suppressing LAMP1 ubiquitination to stabilize lysosomal membranes and sustain autophagic flux.
Shikonin Induces Autophagy and Apoptosis in Esophageal Cancer EC9706 Cells by Regulating the AMPK/mTOR/ULK Axis.
Protective Effects of Isostrictiniin Against High-Fat, High-Sugar Diet-Induced Steatosis in MASLD Mice via Regulation of the AMPK/SREBP-1c/ACC Pathway.
Structural characterization and improves cognitive disorder in ageing mice of a glucomannan from Dendrobium huoshanense.
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Axonal protection by combination of ripasudil and brimonidine with upregulation of p-AMPK in TNF-induced optic nerve degeneration.
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Heme Oxygenase-1-Modified BMMSCs Activate AMPK-Nrf2-FTH1 to Reduce Severe Steatotic Liver Ischemia-Reperfusion Injury.
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
RNF126 contributes to stem cell-like properties and metastasis in hepatocellular carcinoma through ubiquitination and degradation of LKB1.
Therapeutic inhibition of miR-802 protects against obesity through AMPK-mediated regulation of hepatic lipid metabolism.
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1.
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.
Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo.
Wang Z, Ren X, Peng Z, Zeng M, Wang Z, Chen Q, Chen J, Dai X, Christian M, Qie X, He Z
Journal of ethnopharmacology 2026 Jan 10;354:120513
Journal of ethnopharmacology 2026 Jan 10;354:120513
Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer.
Yuan H, Li X, Yu M, Cao Y, Wu L, Shi S, Yang Y, Yu K, Liang B
Theranostics 2025;15(17):8757-8778
Theranostics 2025;15(17):8757-8778
Enhanced bioactivity of honeysuckle-Cassia seeds extracts through Lactobacillus acidophilus and Bacillus subtilis co-fermentation: Impact on alcoholic liver disease and gut microbiota.
Zhou M, Zhang Y, Song Z, Tang S, Liu Z, Pang M, Zhang D, Wu X, Yu X, Wang P, Wei Y
Food chemistry 2025 Sep 15;486:144463
Food chemistry 2025 Sep 15;486:144463
Ganoderic acid a derivative induces apoptosis of cervical cancer cells by inhibiting JNK pathway.
Wang M, Han Q, Zhang X, Dong X, Ran J, Wei F, Luo Y, Sun X
Chinese herbal medicines 2025 Oct;17(4):756-767
Chinese herbal medicines 2025 Oct;17(4):756-767
CANDiT: A machine learning framework for differentiation therapy in colorectal cancer.
Sinha S, Alcantara J, Perry K, Castillo V, Ondersma AK, Banerjee S, McLaren E, Espinoza CR, Taheri S, Vidales E, Tindle C, Adel A, Amirfakhri S, Sawires JR, Yang J, Bouvet M, Ghosh P
Cell reports. Medicine 2025 Nov 18;6(11):102421
Cell reports. Medicine 2025 Nov 18;6(11):102421
Hypoglycemic effect of dietary fibers from Moringa oleifera leaves: In vitro and in vivo studies.
Li X, Yong J, Zhao B, Zhu Y, Luo J, Sheng J, Tian Y
Food research international (Ottawa, Ont.) 2025 May;209:116196
Food research international (Ottawa, Ont.) 2025 May;209:116196
Salidroside alleviates doxorubicin-induced hepatotoxicity via Sestrin2/AMPK-mediated pyroptotic inhibition.
Wang N, Gao Z, Zhan H, Jing L, Meng F, Chen M
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 May;199:115335
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 May;199:115335
Xiasangju alleviates hepatic insulin resistance in db/db mice via AMPK pathway: Mechanisms and active components study.
An Y, Zhao H, He C, Shi L, Su X, Zhang H, Huang Y, Shan Z, Wang M, Du Y, Xie J, Zhao Y, Yang Y, Huang Z, Wan A, Zhao Y, Zhao B
International immunopharmacology 2025 May 27;156:114675
International immunopharmacology 2025 May 27;156:114675
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Wu Y, Duan Z, Qu L, Liu Y, Ma X, Fan D
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway.
Chen M, Liu G, Fang Z, Gao W, Song Y, Lei L, Du X, Li X
Autophagy 2025 Jun;21(6):1316-1334
Autophagy 2025 Jun;21(6):1316-1334
Hawthorn total flavonoids ameliorate hyperlipidemia through AMPK/SREBP1-c and PPARα/PGC-1α/CPT-1A pathway activation and gut microbiota modulation.
Zheng L, Lu Z, Ma Y, Cui P, Zhang X, Gan J, Li G
Journal of the science of food and agriculture 2025 Jun;105(8):4326-4337
Journal of the science of food and agriculture 2025 Jun;105(8):4326-4337
miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice.
Wang Y, Jiang L, Tian JJ, Zhu LL, Dai HJ, Guo C, Zhou LY, Wang L, Lu Y, Zhang Y
Neurochemical research 2025 Jun 5;50(3):180
Neurochemical research 2025 Jun 5;50(3):180
Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a.
Zhang C, Chen L, Jiang Y, Qiu J, Lin Y, Ren G, Xu F, Xi J, Yu Z, Rong X, Dou X
International immunopharmacology 2025 Jun 5;157:114768
International immunopharmacology 2025 Jun 5;157:114768
Shionone Inhibits Glomerular Fibirosis by Suppressing NLRP3 Related Inflammasome though SESN2-NRF2/ HO-1 Pathway.
Xiao T, Zhao H, Wang Y, Chen M, Wang C, Qiao C
Diabetes & metabolism journal 2025 Jan;49(1):34-48
Diabetes & metabolism journal 2025 Jan;49(1):34-48
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Liu X, Guan K, Liu C, Sun Y, Ma Y, Mao K, Li Q, Wang R, Lu W
Journal of dairy science 2025 Dec;108(12):12949-12969
Journal of dairy science 2025 Dec;108(12):12949-12969
SGLT2i continuously prevents cardiac hypertrophy by reducing ferroptosis via AMPK up-regulation.
Zhao BB, Wang J, Zhang LL, Li C, Xue HH, Zhao L, Han QH, Shi HT
Molecular and cellular biochemistry 2025 Aug;480(8):4849-4864
Molecular and cellular biochemistry 2025 Aug;480(8):4849-4864
IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPKα to attenuate hypercholesterolemia.
Li J, Wang M, Qu K, Sun Y, Yin Z, Dong N, Sun X, Xu Y, Chen L, Zhang S, Xian X, Xu S, Ma L, Duan Y, Zhu H
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4047-4063
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4047-4063
LAPTM5 confers cisplatin resistance in NSCLC by suppressing LAMP1 ubiquitination to stabilize lysosomal membranes and sustain autophagic flux.
Wu F, Li C, Song X, Xie L
Cellular signalling 2025 Aug;132:111834
Cellular signalling 2025 Aug;132:111834
Shikonin Induces Autophagy and Apoptosis in Esophageal Cancer EC9706 Cells by Regulating the AMPK/mTOR/ULK Axis.
Zhang J, Guo J, Gu B, Wang F, Li Y, Shang L, Jiang W, Ma J, Wu W
Analytical cellular pathology (Amsterdam) 2024;2024:7752299
Analytical cellular pathology (Amsterdam) 2024;2024:7752299
Protective Effects of Isostrictiniin Against High-Fat, High-Sugar Diet-Induced Steatosis in MASLD Mice via Regulation of the AMPK/SREBP-1c/ACC Pathway.
Yan Q, Li C, Li J, Yao Y, Zhao J
Nutrients 2024 Nov 13;16(22)
Nutrients 2024 Nov 13;16(22)
Structural characterization and improves cognitive disorder in ageing mice of a glucomannan from Dendrobium huoshanense.
Zhang X, Ge R, Wu J, Cai X, Deng G, Lv J, Ma M, Yu N, Yao L, Peng D
International journal of biological macromolecules 2024 Jun;269(Pt 1):131995
International journal of biological macromolecules 2024 Jun;269(Pt 1):131995
Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet.
Zhang B, Zhao W, Song D, Lyu X
Food & function 2024 Aug 27;15(17):8759-8774
Food & function 2024 Aug 27;15(17):8759-8774
Axonal protection by combination of ripasudil and brimonidine with upregulation of p-AMPK in TNF-induced optic nerve degeneration.
Otsubo M, Sase K, Tsukahara C, Fujita N, Arizono I, Tokuda N, Kitaoka Y
International ophthalmology 2024 Apr 10;44(1):173
International ophthalmology 2024 Apr 10;44(1):173
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Jiang W, Zhang M, Gao C, Yan C, Gao R, He Z, Wei X, Xiong J, Ruan Z, Yang Q, Li J, Li Q, Zhong Z, Zhang M, Yuan Q, Hu H, Wang S, Hu MM, Cai C, Wu GS, Jiang C, Zhang YL, Zhang CS, Zhang J
The EMBO journal 2023 Oct 16;42(20):e113743
The EMBO journal 2023 Oct 16;42(20):e113743
Heme Oxygenase-1-Modified BMMSCs Activate AMPK-Nrf2-FTH1 to Reduce Severe Steatotic Liver Ischemia-Reperfusion Injury.
Tian X, Wang Y, Yuan M, Zheng W, Zuo H, Zhang X, Song H
Digestive diseases and sciences 2023 Nov;68(11):4196-4211
Digestive diseases and sciences 2023 Nov;68(11):4196-4211
Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy.
Xiao C, Sun Y, Fan J, Nguyen W, Chen S, Long Y, Chen W, Zhu A, Liu B
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
Acta pharmaceutica Sinica. B 2023 Nov;13(11):4591-4606
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151
Mulberry leaves attenuate D-galactose-induced aging in vivo and in vitro.
Zhu Y, Han Y, Wang W, Liang G, Qi J
Journal of ethnopharmacology 2023 Jul 15;311:116286
Journal of ethnopharmacology 2023 Jul 15;311:116286
RNF126 contributes to stem cell-like properties and metastasis in hepatocellular carcinoma through ubiquitination and degradation of LKB1.
Huang J, Li Y, Zheng M, He H, Xu D, Tian D
Human cell 2022 Nov;35(6):1869-1884
Human cell 2022 Nov;35(6):1869-1884
Therapeutic inhibition of miR-802 protects against obesity through AMPK-mediated regulation of hepatic lipid metabolism.
Ni Y, Xu Z, Li C, Zhu Y, Liu R, Zhang F, Chang H, Li M, Sheng L, Li Z, Hou M, Chen L, You H, McManus DP, Hu W, Duan Y, Liu Y, Ji M
Theranostics 2021;11(3):1079-1099
Theranostics 2021;11(3):1079-1099
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1.
Zheng Z, Li Y, Fan S, An J, Luo X, Liang M, Zhu F, Huang K
Cell death & disease 2021 Mar 3;12(3):228
Cell death & disease 2021 Mar 3;12(3):228
CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.
Li Q, Wang Y, Wu S, Zhou Z, Ding X, Shi R, Thorne RF, Zhang XD, Hu W, Wu M
Cell metabolism 2019 Jul 2;30(1):157-173.e7
Cell metabolism 2019 Jul 2;30(1):157-173.e7
Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo.
Shen CT, Wei WJ, Qiu ZL, Song HJ, Zhang XY, Sun ZK, Luo QY
Journal of molecular endocrinology 2017 Jan;58(1):15-23
Journal of molecular endocrinology 2017 Jan;58(1):15-23
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The AMPK beta 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AMPK beta 1. This antibody recognizes human,mouse,rat antigen. The AMPK beta 1 antibody has been validated for the following applications: ELISA, WB analysis.