17038-1-AP

antibody from Proteintech Group

Targeting: CXCL8 3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1

Provider product page for 17038-1-AP

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [29]
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Product number: 17038-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#17038-1-AP, RRID:AB_2126217
Product name: CXCL8/IL-8 antibody
Antibody type: Polyclonal
Description: CXCL8/IL-8 antibody (Cat. #17038-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CXCL8 protein structure - 17038-1-AP shown in red.

Submitted references Potential mechanisms of zinc sulfate in inhibiting porcine reproductive and respiratory syndrome virus replication: attenuation of oxidative stress, inflammatory response, and apoptosis.

Yang H, Zhang C, Li Q, Wu Z, Sun N, Yin W, Fan K, Li H
Frontiers in veterinary science 2025;12:1663508

Identification of CXCL8 as a potential gene associated with lymph node metastasis in papillary thyroid carcinoma through bioinformatics analysis.

Liu F, Zhang W, Gao X, Xiang Q, Li Z, Zhou Q, Wei X, Liu R
Scientific reports 2025 Nov 25;15(1):41771

FDA-approved phensuximide inhibits RIPK1-dependent immunogenic cell death.

Kim BJ, Hong SM, Noh HJ, Kim J, Seon SY, Lee JE, Jeong DH, Park JM, Park S, Lee S, Kang J, Lee D, Morgan MJ, Kim YS
Cell death & disease 2025 Jun 2;16(1):426

A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression.

Tang Z, Hu J, Li XC, Wang W, Zhang HY, Guo YY, Shuai X, Chu Q, Xie C, Lin D, Zhong B
Developmental cell 2025 Feb 3;60(3):379-395.e8

miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma.

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Journal of experimental & clinical cancer research : CR 2025 Feb 22;44(1):65

GADD45β inhibits RIPK3-mediated NF-κB activation by interfering with NEMO-RIPK1-RIPK3 interactions.

Casale C, Colella A, Cruoglio M, Mirra S, Iaccarino E, Lioi MB, Fusco F, Sandomenico A, Leonardi A, Zazzeroni F, Pescatore A
Cell death discovery 2025 Dec 7;12(1):41

Quercetin alleviates ulcerative colitis through inhibiting CXCL8-CXCR1/2 axis: a network and transcriptome analysis.

Jiang Z, Yan M, Qin Y, Liu Z, Duan Y, Wang Y, Zhang R, Lin W, Li Y, Xie T, Ke J
Frontiers in pharmacology 2024;15:1485255

Identification of potential biomarkers of gout through weighted gene correlation network analysis.

Wang X, Yang B, Xiong T, Qiu Y, Qin Y, Liang X, Lu D, Yang X
Frontiers in immunology 2024;15:1367019

Mechanistic insights into lethal hyper progressive disease induced by PD-L1 inhibitor in metastatic urothelial carcinoma.

Nishimura K, Takahara K, Komura K, Ishida M, Hirosuna K, Maenosono R, Ajiro M, Sakamoto M, Iwatsuki K, Nakajima Y, Tsujino T, Taniguchi K, Tanaka T, Inamoto T, Hirose Y, Ono F, Kondo Y, Yoshimi A, Azuma H
NPJ precision oncology 2024 Sep 17;8(1):206

Inactivation of Myostatin Delays Senescence via TREX1-SASP in Bovine Skeletal Muscle Cells.

Yang M, Gao L, Gao Y, Hao Z, Zhou X, Su G, Bai C, Wei Z, Liu X, Yang L, Li G
International journal of molecular sciences 2024 May 12;25(10)

NUCB2 inhibition antagonizes osteosarcoma progression and promotes anti-tumor immunity through inactivating NUCKS1/CXCL8 axis.

Ji R, Wang Y, Pan D, Han J, Wang Y, Zheng S, Zhao W, Li X, Han C, Zhang L
Cancer letters 2024 Jun 1;591:216893

Pancreatobiliary reflux increases macrophage-secreted IL-8 and activates the PI3K/NFκB pathway to promote cholangiocarcinoma progression.

Wu T, Gao R, Wang X, Guo D, Xie Y, Dong B, Hao X, Zhu C
Translational oncology 2024 Jul;45:101967

Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.

Wu W, Li G, Dong S, Huihan Chu C, Ma S, Zhang Z, Yuan S, Wu J, Guo Z, Shen Y, Wang J, Tang C
International immunopharmacology 2024 Jan 25;127:111423

Sodium-glucose co-transporter 2 inhibitor canagliflozin modulates myocardial metabolism and inflammation in a swine model for chronic myocardial ischemia.

Harris DD, Sabe SA, Xu CM, Sabra M, Broadwin M, Malhotra A, Li JW, Abid MR, Sellke FW
Surgery 2024 Feb;175(2):265-270

Phthalate exposure aggravates periodontitis by activating NFκB pathway.

Wu W, Jiang W, Zhou Y, Zhang Z, Li G, Tang C
Ecotoxicology and environmental safety 2024 Apr 15;275:116252

Comprehensive analysis of senescence-related genes and immune infiltration in intervertebral disc degeneration: a meta-data approach utilizing bulk and single-cell RNA sequencing data.

Deng YJ, Wang XG, Li Z, Wang B, Li J, Ma J, Xue X, Tian X, Liu QC, Liu JY, Zhang Y, Yuan B
Frontiers in molecular biosciences 2023;10:1296782

IL-8 Is Upregulated in the Tissue-Derived EVs of Odontogenic Keratocysts.

Liu JF, Zhang CX, Li RF, Man QW
BioMed research international 2022;2022:9453270

Mesenchymal stem cells derived from adipose accelerate the progression of colon cancer by inducing a MT-CAFs phenotype via TRPC3/NF-KB axis.

Xue C, Gao Y, Li X, Zhang M, Yang Y, Han Q, Sun Z, Bai C, Zhao RC
Stem cell research & therapy 2022 Jul 23;13(1):335

Endometrial stromal cell ferroptosis promotes angiogenesis in endometriosis.

Li G, Lin Y, Zhang Y, Gu N, Yang B, Shan S, Liu N, Ouyang J, Yang Y, Sun F, Xu H
Cell death discovery 2022 Jan 17;8(1):29

miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.

Li C, Zheng H, Xiong J, Huang Y, Li H, Jin H, Ai S, Wang Y, Su T, Sun G, Xiao X, Fu T, Wang Y, Gao X, Liang P
Cell death & disease 2022 Aug 12;13(8):699

The role of PKM2 nuclear translocation in the constant activation of the NF-κB signaling pathway in cancer-associated fibroblasts.

Gu J, Li X, Zhao L, Yang Y, Xue C, Gao Y, Li J, Han Q, Sun Z, Bai C, Zhao RC
Cell death & disease 2021 Mar 17;12(4):291

RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment.

Park HH, Kim HR, Park SY, Hwang SM, Hong SM, Park S, Kang HC, Morgan MJ, Cha JH, Lee D, Roe JS, Kim YS
Molecular cancer 2021 Aug 21;20(1):107

MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.

Shen XF, Cheng Y, Dong QR, Zheng MQ
Biochemical and biophysical research communications 2020 Jun 25;527(2):458-465

LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.

Sun X, Thorne RF, Zhang XD, He M, Li J, Feng S, Liu X, Wu M
EMBO reports 2020 Apr 3;21(4):e48796

Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis.

Zhang T, Liu L, Lai W, Zeng Y, Xu H, Lan Q, Su P, Chu Z
Oncology reports 2019 May;41(5):2790-2802

Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression.

Zhu K, Liang W, Ma Z, Xu D, Cao S, Lu X, Liu N, Shan B, Qian L, Yuan J
Cell death & disease 2018 May 1;9(5):500

Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study.

Tabatabaei P, Visse E, Bergström P, Brännström T, Siesjö P, Bergenheim AT
Journal of neuro-oncology 2017 Jan;131(1):83-92

Expression, purification, and characterization of rhTyrRS.

Lang Y, Zhang Y, Zhan L, Feng Z, Zhou X, Yu M, Mo W
BMC biotechnology 2014 Jul 15;14:64

Molecular crosstalk between cancer cells and tumor microenvironment components suggests potential targets for new therapeutic approaches in mobile tongue cancer.

Dayan D, Salo T, Salo S, Nyberg P, Nurmenniemi S, Costea DE, Vered M
Cancer medicine 2012 Oct;1(2):128-40

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