CAPN10

gene product
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010]
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147 antibodies from 23 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
5 antibodies
antibodies-online
55 antibodies
Abnova Corporation
4 antibodies
Atlas Antibodies
2 antibodies
GeneTex
2 antibodies
Invitrogen Antibodies
3 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
4 antibodies
Biorbyt
5 antibodies
LifeSpan BioSciences, Inc.
38 antibodies
Creative Biolabs
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
OriGene
1 antibody
St John's Laboratory
3 antibodies
RabMAbs
2 antibodies
Boster Biological Technology
1 antibody
ProSci
1 antibody
MyBioSource
5 antibodies
Creative Diagnostics
3 antibodies
Sigma-Aldrich
5 antibodies
Abbiotec
1 antibody
Abbexa
1 antibody
Acris Antibodies GmbH
1 antibody