ABIN2841982

antibody from antibodies-online

Targeting: COPS3 CSN3, SGN3

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN2841982

Provider

antibodies-online

Product name

anti-COP9 Constitutive Photomorphogenic Homolog Subunit 3 (Arabidopsis) (COPS3) (AA 98-130), (Center) antibody

Antibody type

Polyclonal

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 98-130, Center

Antibody clone number

RB17614

Vial size

80 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation.

Henriksen J, Aagesen TH, Maelandsmo GM, Lothe RA, Myklebost O, Forus A
Oncogene 2003 Aug 14;22(34):5358-61

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COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system.

Bech-Otschir D, Kraft R, Huang X, Henklein P, Kapelari B, Pollmann C, Dubiel W
The EMBO journal 2001 Apr 2;20(7):1630-9

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Subunit 3 of the COP9 signal transduction complex is conserved from plants to humans and maps within the smith-magenis syndrome critical region in 17p11.2.

Potocki L, Chen KS, Lupski JR
Genomics 1999 Apr 1;57(1):180-2

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB