Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN360225 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-COP9 Constitutive Photomorphogenic Homolog Subunit 3 (Arabidopsis) (COPS3) (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Middle Region
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation.
COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system.
Subunit 3 of the COP9 signal transduction complex is conserved from plants to humans and maps within the smith-magenis syndrome critical region in 17p11.2.
Henriksen J, Aagesen TH, Maelandsmo GM, Lothe RA, Myklebost O, Forus A
Oncogene 2003 Aug 14;22(34):5358-61
Oncogene 2003 Aug 14;22(34):5358-61
COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system.
Bech-Otschir D, Kraft R, Huang X, Henklein P, Kapelari B, Pollmann C, Dubiel W
The EMBO journal 2001 Apr 2;20(7):1630-9
The EMBO journal 2001 Apr 2;20(7):1630-9
Subunit 3 of the COP9 signal transduction complex is conserved from plants to humans and maps within the smith-magenis syndrome critical region in 17p11.2.
Potocki L, Chen KS, Lupski JR
Genomics 1999 Apr 1;57(1):180-2
Genomics 1999 Apr 1;57(1):180-2
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