Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60618 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- SCD polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human SCD
- Description
- Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters. SCD plays a major role in the triacylglycerol and phospholipid secretion process and in mechanisms of cellular cholesterol homeostasis. It is subject to rapid turnover in the cell and, as such, represents a model for studying selective degradation of short-lived proteins of the ER. SCD is also an important regulator of membrane fluidity. An increase in expression levels of SCD is observed in cells which are induced to differentiate into adipocytes and in certain tumor cell lines. Due to gene duplication events, the number of genes in the SCD family differs between species. Their expression patterns are affected by the level of unsaturated fatty acids in the diet of the animal.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of SCD pAb at 1:500 dilutionLane1:Hela whole cell lysateLane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate