BS7251

antibody from Bioworld Technology, Inc

Targeting: BIK NBK

Immunohistochemistry

Antibody data

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Validation data

Product number: BS7251 - Provider product page
Provider: Bioworld Technology, Inc
Product name: BIK polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human BIK.
Description: Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2. Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins . Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity.
Reactivity: Human
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

BIK protein structure - BS7251 shown in red.