CABT-BL3161

antibody from Creative Diagnostics

Targeting: RNASEH2A AGS4, RNASEHI, RNHIA, RNHL

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-BL3161

Provider

Creative Diagnostics

Product name

Anti-RNASEH2A monoclonal antibody, clone 4H6-G6

Antibody type

Monoclonal

Description

The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4H6-G6

Storage

Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.