Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 15934-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15934-1-AP, RRID:AB_2095546
- Product name
- DNASE2 antibody
- Antibody type
- Polyclonal
- Description
- DNASE2 antibody (Cat. #15934-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ZNRF2-mediated CD-M6PR degradation and lysosomal dysfunction aggravate cellular senescence and aging.
S-nitrosation in endothelium: different outcomes of NRF2 and GSNOR loss.
Brucea javanica oil emulsion ameliorates ulcerative colitis by upregulating Deoxyribonuclease 2 to suppress cytosolic DNA-sensing signaling.
Microglial double stranded DNA accumulation induced by DNase II deficiency drives neuroinflammation and neurodegeneration.
Angelica sinensis polysaccharides ameliorate 5-FU-induced stress anemia via promoting extramedullary erythroblastic island central macrophage-mediated erythroid differentiation.
Neuronal double-stranded DNA accumulation induced by DNase II deficiency drives tau phosphorylation and neurodegeneration.
Mangiferin Protects DNase 2 Abundance via Nrf2 Activation to Prevent Cytosolic mtDNA Accumulation during Liver Injury.
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress-induced senescence.
Zhao T, Xu W, Wang F, Chen H, Gong H, Yang Y, Huang N, Yang M, Zhang J, Gong C, Huang X, Li Y, Zhang C, Xiao H
GeroScience 2026 May 1;
GeroScience 2026 May 1;
S-nitrosation in endothelium: different outcomes of NRF2 and GSNOR loss.
Kopacz A, Kloska D, Kraszewska I, Targosz-Korecka M, Kubisiak A, Jankowska U, Skupien-Rabian B, Grochot-Przeczek A, Jozkowicz A
Free radical biology & medicine 2026 Feb 16;244:323-335
Free radical biology & medicine 2026 Feb 16;244:323-335
Brucea javanica oil emulsion ameliorates ulcerative colitis by upregulating Deoxyribonuclease 2 to suppress cytosolic DNA-sensing signaling.
Ren M, Liu C, Lai J, Huang W, Wang J, Tu J, Yang B, Su Z, Han Q, Lai Z, Chen J, Liang Q, Xie Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157980
Microglial double stranded DNA accumulation induced by DNase II deficiency drives neuroinflammation and neurodegeneration.
Li LJ, Liang SY, Sun XY, Zhu J, Niu XY, Du XY, Huang YR, Liu RT
Journal of neuroinflammation 2025 Jan 20;22(1):11
Journal of neuroinflammation 2025 Jan 20;22(1):11
Angelica sinensis polysaccharides ameliorate 5-FU-induced stress anemia via promoting extramedullary erythroblastic island central macrophage-mediated erythroid differentiation.
Wang B, Jiang H, Sun N, Wang Z, Wang C, Yang T, Wang Y, Wang L
International immunopharmacology 2024 Dec 5;142(Pt A):113061
International immunopharmacology 2024 Dec 5;142(Pt A):113061
Neuronal double-stranded DNA accumulation induced by DNase II deficiency drives tau phosphorylation and neurodegeneration.
Li LJ, Sun XY, Huang YR, Lu S, Xu YM, Yang J, Xie XX, Zhu J, Niu XY, Wang D, Liang SY, Du XY, Hou SJ, Yu XL, Liu RT
Translational neurodegeneration 2024 Aug 2;13(1):39
Translational neurodegeneration 2024 Aug 2;13(1):39
Mangiferin Protects DNase 2 Abundance via Nrf2 Activation to Prevent Cytosolic mtDNA Accumulation during Liver Injury.
Li L, Zhen Y, Chen X, Cao L, Song J, Liu X, Wang M
Molecular nutrition & food research 2023 Jul;67(14):e2200885
Molecular nutrition & food research 2023 Jul;67(14):e2200885
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Zhao D, Gao Y, Su Y, Zhou Y, Yang T, Li Y, Wang Y, Sun Y, Chen L, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Pharmacological research 2023 Jan;187:106590
Pharmacological research 2023 Jan;187:106590
Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress-induced senescence.
Han X, Chen H, Gong H, Tang X, Huang N, Xu W, Tai H, Zhang G, Zhao T, Gong C, Wang S, Yang Y, Xiao H
The Journal of biological chemistry 2020 Apr 3;295(14):4451-4463
The Journal of biological chemistry 2020 Apr 3;295(14):4451-4463
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The DNASE2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DNASE2. This antibody recognizes human,mouse,rat antigen. The DNASE2 antibody has been validated for the following applications: ELISA, WB analysis.