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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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- Product number
- MA5-16936 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD4 Monoclonal Antibody (RPA-T4)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. We recommend the use of acetone fixation for frozen sections. A suggested positive control for immunohistochemical applications is human lymphatic tissue. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- RPA-T4
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients.
Low-dose interleukin-2 promotes STAT-5 phosphorylation, T(reg) survival and CTLA-4-dependent function in autoimmune liver diseases.
Casein kinase 2 controls the survival of normal thymic and leukemic γδ T cells via promotion of AKT signaling.
Targeting type I interferon-mediated activation restores immune function in chronic HIV infection.
The RNA-Binding Protein, Polypyrimidine Tract-Binding Protein 1 (PTBP1) Is a Key Regulator of CD4 T Cell Activation.
Trained immunity in newborn infants of HBV-infected mothers.
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.
Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features.
Mature dendritic cells in inflamed human pulps beneath deep caries.
Etiological treatment during early chronic indeterminate Chagas disease incites an activated status on innate and adaptive immunity associated with a type 1-modulated cytokine pattern.
Activation/modulation of adaptive immunity emerges simultaneously after 17DD yellow fever first-time vaccination: is this the key to prevent severe adverse reactions following immunization?
Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo.
Kim JM, Kwon CHD, Joh JW, Sinn DH, Choi GS, Park JB, Kang ES, Lee SK
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2017;26(3):221-228
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2017;26(3):221-228
Low-dose interleukin-2 promotes STAT-5 phosphorylation, T(reg) survival and CTLA-4-dependent function in autoimmune liver diseases.
Jeffery HC, Jeffery LE, Lutz P, Corrigan M, Webb GJ, Hirschfield GM, Adams DH, Oo YH
Clinical and experimental immunology 2017 Jun;188(3):394-411
Clinical and experimental immunology 2017 Jun;188(3):394-411
Casein kinase 2 controls the survival of normal thymic and leukemic γδ T cells via promotion of AKT signaling.
Ribeiro ST, Tesio M, Ribot JC, Macintyre E, Barata JT, Silva-Santos B
Leukemia 2017 Jul;31(7):1603-1610
Leukemia 2017 Jul;31(7):1603-1610
Targeting type I interferon-mediated activation restores immune function in chronic HIV infection.
Zhen A, Rezek V, Youn C, Lam B, Chang N, Rick J, Carrillo M, Martin H, Kasparian S, Syed P, Rice N, Brooks DG, Kitchen SG
The Journal of clinical investigation 2017 Jan 3;127(1):260-268
The Journal of clinical investigation 2017 Jan 3;127(1):260-268
The RNA-Binding Protein, Polypyrimidine Tract-Binding Protein 1 (PTBP1) Is a Key Regulator of CD4 T Cell Activation.
La Porta J, Matus-Nicodemos R, Valentín-Acevedo A, Covey LR
PloS one 2016;11(8):e0158708
PloS one 2016;11(8):e0158708
Trained immunity in newborn infants of HBV-infected mothers.
Hong M, Sandalova E, Low D, Gehring AJ, Fieni S, Amadei B, Urbani S, Chong YS, Guccione E, Bertoletti A
Nature communications 2015 Mar 25;6:6588
Nature communications 2015 Mar 25;6:6588
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.
Severson JJ, Serracino HS, Mateescu V, Raeburn CD, McIntyre RC Jr, Sams SB, Haugen BR, French JD
Cancer immunology research 2015 Jun;3(6):620-30
Cancer immunology research 2015 Jun;3(6):620-30
Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features.
Arlehamn CL, Seumois G, Gerasimova A, Huang C, Fu Z, Yue X, Sette A, Vijayanand P, Peters B
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 15;193(6):2931-40
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 15;193(6):2931-40
Mature dendritic cells in inflamed human pulps beneath deep caries.
Harmon MA, Tew JG, Best AM, Hahn CL
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2009 May;107(5):727-32
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2009 May;107(5):727-32
Etiological treatment during early chronic indeterminate Chagas disease incites an activated status on innate and adaptive immunity associated with a type 1-modulated cytokine pattern.
Sathler-Avelar R, Vitelli-Avelar DM, Massara RL, de Lana M, Pinto Dias JC, Teixeira-Carvalho A, Elói-Santos SM, Martins-Filho OA
Microbes and infection 2008 Feb;10(2):103-13
Microbes and infection 2008 Feb;10(2):103-13
Activation/modulation of adaptive immunity emerges simultaneously after 17DD yellow fever first-time vaccination: is this the key to prevent severe adverse reactions following immunization?
Martins MA, Silva ML, Marciano AP, Peruhype-Magalhães V, Eloi-Santos SM, Ribeiro jG, Correa-Oliveira R, Homma A, Kroon EG, Teixeira-Carvalho A, Martins-Filho OA
Clinical and experimental immunology 2007 Apr;148(1):90-100
Clinical and experimental immunology 2007 Apr;148(1):90-100
Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo.
Schreiner B, Wischhusen J, Mitsdoerffer M, Schneider D, Bornemann A, Melms A, Tolosa E, Weller M, Wiendl H
Glia 2003 Dec;44(3):296-301
Glia 2003 Dec;44(3):296-301
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