Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 19068-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19068-1-AP, RRID:AB_10603357
- Product name
- CD4 antibody
- Antibody type
- Polyclonal
- Description
- CD4 antibody (Cat. #19068-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Oxidative Stress-Responsive Apoptosis Inducing Protein (ORAIP) Plays a Critical Role in Dextran Sulfate Sodium-Induced Murine Model of Ulcerative Colitis.
Modified Biejia Jianwan decoction restrains PD-L1-mediated immune evasion through the HIF-1α/STAT3/NF-κB signaling pathway.
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Spastin is required for human immunodeficiency virus-1 efficient replication through cooperation with the endosomal sorting complex required for transport (ESCRT) protein.
Systematic analysis identifies REST as an oncogenic and immunological biomarker in glioma.
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Distribution and chemotactic mechanism of CD4(+) T cells in traumatic tracheal stenosis.
Transmembrane Protein 170B is a Prognostic Biomarker and Associated With Immune Infiltrates in Pancreatic Adenocarcinoma.
Identification and experimental validation of a tumor-infiltrating lymphocytes-related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma.
A Toxin-Conjugated Recombinant Protein Targeting gp120 and gp41 for Inactivating HIV-1 Virions and Killing Latency-Reversing Agent-Reactivated Latent Cells.
Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
Human Milk Oligosaccharide 2'-Fucosyllactose Induces Neuroprotection from Intracerebral Hemorrhage Stroke.
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway.
Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice.
Calpain mediated expansion of CD4+ cytotoxic T cells in rodent models of Parkinson's disease.
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer.
Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Curative effect of endostar combined with oxaliplatin in the treatment of primary hepatic carcinoma and its influence on immune cells.
The combination of indirubin and isatin attenuates dextran sodium sulfate induced ulcerative colitis in mice.
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse.
CALCB splice region pathogenic variants leading to plasma cell neurotropic enrichment in type 1 autoimmune pancreatitis.
Adropin deficiency worsens HFD-induced metabolic defects.
Nakajima A, Shibuya T, Yao T, Fujimura T, Murayama K, Okumura K, Nagahara A, Seko Y
Medicina (Kaunas, Lithuania) 2024 Mar 26;60(4)
Medicina (Kaunas, Lithuania) 2024 Mar 26;60(4)
Modified Biejia Jianwan decoction restrains PD-L1-mediated immune evasion through the HIF-1α/STAT3/NF-κB signaling pathway.
Tian X, Liu F, Wang Z, Zhang J, Liu Q, Zhang Y, Zhang D, Huang C, Zhao J, Jiang S
Journal of ethnopharmacology 2024 Mar 25;322:117577
Journal of ethnopharmacology 2024 Mar 25;322:117577
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Zhang L, Zhao X, Niu Y, Ma X, Yuan W, Ma J
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Spastin is required for human immunodeficiency virus-1 efficient replication through cooperation with the endosomal sorting complex required for transport (ESCRT) protein.
Shen W, Liu C, Hu Y, Ding Q, Feng J, Liu Z, Kong X
Virologica Sinica 2023 Jun;38(3):448-458
Virologica Sinica 2023 Jun;38(3):448-458
Systematic analysis identifies REST as an oncogenic and immunological biomarker in glioma.
Wang G, Yang X, Qi M, Li M, Dong M, Xu R, Zhang C
Scientific reports 2023 Feb 21;13(1):3023
Scientific reports 2023 Feb 21;13(1):3023
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
Wang Z, Yang Z, Qu C, Li J, Wang X
International urology and nephrology 2023 Aug;55(8):1957-1970
International urology and nephrology 2023 Aug;55(8):1957-1970
Distribution and chemotactic mechanism of CD4(+) T cells in traumatic tracheal stenosis.
Feng T, Chen Y, Wei J, Tan S, Guangnan L
Immunity, inflammation and disease 2023 Aug;11(8):e916
Immunity, inflammation and disease 2023 Aug;11(8):e916
Transmembrane Protein 170B is a Prognostic Biomarker and Associated With Immune Infiltrates in Pancreatic Adenocarcinoma.
Zhang Z, Shang J, Dai Z, Yao Y, Shi Y, Zhong D, Liang Y, Lai C, Yang Q, Feng T, Huang X
Frontiers in genetics 2022;13:848391
Frontiers in genetics 2022;13:848391
Identification and experimental validation of a tumor-infiltrating lymphocytes-related long noncoding RNA signature for prognosis of clear cell renal cell carcinoma.
Deng Y, Guo K, Tang Z, Feng Y, Cai S, Ye J, Xi Y, Li J, Liu R, Cai C, Tan Z, Zhang Y, Han Z, Zeng G, Zhong W
Frontiers in immunology 2022;13:1046790
Frontiers in immunology 2022;13:1046790
A Toxin-Conjugated Recombinant Protein Targeting gp120 and gp41 for Inactivating HIV-1 Virions and Killing Latency-Reversing Agent-Reactivated Latent Cells.
Wang X, Xu W, Liu Z, Wu Y, Wang Q, Cao M, Ying T, He N, Lu L, Jiang S
mBio 2022 Feb 22;13(1):e0338421
mBio 2022 Feb 22;13(1):e0338421
Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
Xu N, Hu A, Pu X, Li J, Wang X, Wang J, Huang Z, Liao X, Yin G
ACS applied materials & interfaces 2022 Apr 13;14(14):15894-15910
ACS applied materials & interfaces 2022 Apr 13;14(14):15894-15910
Human Milk Oligosaccharide 2'-Fucosyllactose Induces Neuroprotection from Intracerebral Hemorrhage Stroke.
Hung TW, Wu KJ, Wang YS, Bae EK, Song Y, Yoon J, Yu SJ
International journal of molecular sciences 2021 Sep 13;22(18)
International journal of molecular sciences 2021 Sep 13;22(18)
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer.
Jin F, Qi J, Liu D, You Y, Shu G, Du Y, Wang J, Xu X, Ying X, Ji J, Du Y
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
Journal of controlled release : official journal of the Controlled Release Society 2021 Sep 10;337:90-104
Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway.
Xu J, Xiong H, Zhao Z, Luo M, Ju Y, Yang G, Mei Z
Food & function 2021 May 21;12(10):4556-4569
Food & function 2021 May 21;12(10):4556-4569
Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice.
Wang YS, Hung TW, Bae EK, Wu KJ, Hsieh W, Yu SJ
CNS neuroscience & therapeutics 2021 Jul;27(7):831-841
CNS neuroscience & therapeutics 2021 Jul;27(7):831-841
Calpain mediated expansion of CD4+ cytotoxic T cells in rodent models of Parkinson's disease.
Haque A, Samantaray S, Knaryan VH, Capone M, Hossain A, Matzelle D, Chandran R, Shields DC, Farrand AQ, Boger HA, Banik NL
Experimental neurology 2020 Aug;330:113315
Experimental neurology 2020 Aug;330:113315
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer.
Liu Q, Guo L, Zhang S, Wang J, Lin X, Gao F
Molecular medicine (Cambridge, Mass.) 2019 Sep 14;25(1):44
Molecular medicine (Cambridge, Mass.) 2019 Sep 14;25(1):44
Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice.
Fu R, Jiang Y, Zhou J, Zhang J
Molecular medicine reports 2019 May;19(5):4011-4018
Molecular medicine reports 2019 May;19(5):4011-4018
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Cao Z, Ji J, Zhang C, Wang F, Xu H, Yu Y, Sun Y
Cancer medicine 2019 Mar;8(3):1004-1012
Cancer medicine 2019 Mar;8(3):1004-1012
Curative effect of endostar combined with oxaliplatin in the treatment of primary hepatic carcinoma and its influence on immune cells.
Lei C, Ren D, Fu M, Sun C, Ren H, Pan Q, Li Y
Oncology letters 2019 Apr;17(4):3665-3670
Oncology letters 2019 Apr;17(4):3665-3670
The combination of indirubin and isatin attenuates dextran sodium sulfate induced ulcerative colitis in mice.
Gao W, Zhang L, Wang X, Yu L, Wang C, Gong Y
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):636-645
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):636-645
PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse.
Zheng B, Ren T, Huang Y, Sun K, Wang S, Bao X, Liu K, Guo W
Journal of hematology & oncology 2018 Feb 6;11(1):16
Journal of hematology & oncology 2018 Feb 6;11(1):16
CALCB splice region pathogenic variants leading to plasma cell neurotropic enrichment in type 1 autoimmune pancreatitis.
Liu QC, Chen F, Wu CY, Gao F, Zhuang ZH, Chen JT, Cai B, Zhang T, Guo L, Lin LQ, Zhao CF, Lin XH
Cell death & disease 2017 Feb 2;8(2):e2591
Cell death & disease 2017 Feb 2;8(2):e2591
Adropin deficiency worsens HFD-induced metabolic defects.
Chen S, Zeng K, Liu QC, Guo Z, Zhang S, Chen XR, Lin JH, Wen JP, Zhao CF, Lin XH, Gao F
Cell death & disease 2017 Aug 24;8(8):e3008
Cell death & disease 2017 Aug 24;8(8):e3008
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The CD4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD4. This antibody recognizes human, mouse, rat antigen. The CD4 antibody has been validated for the following applications: ELISA, WB analysis.