Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 300519 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#300519, RRID:AB_389311
- Product name
- Alexa Fluor® 488 anti-human CD4 [RPA-T4]
- Antibody type
- Monoclonal
- Antigen
- CD4
- Description
- CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Induction of Th1/Th17 immune response by Mycobacterium tuberculosis: role of dectin-1, Mannose Receptor, and DC-SIGN.
Zenaro E, Donini M, Dusi S
Journal of leukocyte biology 2009 Dec;86(6):1393-401
Journal of leukocyte biology 2009 Dec;86(6):1393-401
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with RPA-T4 Alexa Flour® 488
- Conjugate
- Green dye