HPA004726

antibody from Atlas Antibodies

Targeting: VCAN CSPG2, PG-M

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA004726

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA004726, RRID:AB_1080561

Product name

Anti-VCAN

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human VCAN, Gene description: versican, Alternative Gene Names: CSPG2, PG-M, Validated applications: IHC, Uniprot ID: P13611, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

B cell–based therapy produces antibodies that inhibit glioblastoma growth

Wang S, Castro B, Katz J, Arrieta V, Najem H, Vazquez-Cervantes G, Wan H, Olson I, Hou D, Dapash M, Billingham L, Chia T, Wei C, Rashidi A, Platanias L, McCortney K, Horbinski C, Stupp R, Zhang P, Ahmed A, Sonabend A, Heimberger A, Lesniak M, Riviere-Cazaux C, Burns T, Miska J, Fischietti M, Lee-Chang C
Journal of Clinical Investigation 2024;134(20)

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TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer.

Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, Fukai S, Endo E, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
Cancers 2023 Oct 11;15(20)

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A cellular hierarchy in melanoma uncouples growth and metastasis

Karras P, Bordeu I, Pozniak J, Nowosad A, Pazzi C, Van Raemdonck N, Landeloos E, Van Herck Y, Pedri D, Bervoets G, Makhzami S, Khoo J, Pavie B, Lamote J, Marin-Bejar O, Dewaele M, Liang H, Zhang X, Hua Y, Wouters J, Browaeys R, Bergers G, Saeys Y, Bosisio F, van den Oord J, Lambrechts D, Rustgi A, Bechter O, Blanpain C, Simons B, Rambow F, Marine J
Nature 2022;610(7930):190-198

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Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion

Murray E, Menezes S, Henry J, Williams J, Alba-Castellón L, Baskaran P, Quétier I, Desai A, Marshall J, Rosewell I, Tatari M, Rajeeve V, Khan F, Wang J, Kotantaki P, Tyler E, Singh N, Reader C, Carter E, Hodivala-Dilke K, Grose R, Kocher H, Gavara N, Pearce O, Cutillas P, Marshall J, Cameron A
Cell Reports 2022;38(4):110227

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Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma

de Souza Neto O, Thais Fuzii H, Vieira Da Silva S, Morais Freitas V, Viana Pinheiro J, Lombardi T
International Journal of Dentistry 2022;2022

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A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion

Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler E, Thomas M, Boot G, Mackerodt J, Lockley M, Knight M, Balkwill F, Pearce O
iScience 2021;24(6):102676

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Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer

Delaine-Smith R, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones R, Lecker L, Pearce O, Knight M, Balkwill F
iScience 2021;24(6):102674

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Stromal expression of cancer‑associated fibroblast‑related molecules, versican and lumican, is strongly associated with worse relapse‑free and overall survival times in patients with esophageal squamous cell carcinoma

Yamauchi N, Kanke Y, Saito K, Okayama H, Yamada S, Nakajima S, Endo E, Kase K, Yamada L, Nakano H, Matsumoto T, Hanayama H, Watanabe Y, Hayase S, Saito M, Saze Z, Mimura K, Momma T, Oki S, Hashimoto Y, Kono K
Oncology Letters 2021;21(6)

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Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment

Maniati E, Berlato C, Gopinathan G, Heath O, Kotantaki P, Lakhani A, McDermott J, Pegrum C, Delaine-Smith R, Pearce O, Hirani P, Joy J, Szabova L, Perets R, Sansom O, Drapkin R, Bailey P, Balkwill F
Cell Reports 2020;30(2):525-540.e7

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Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein

Bang-Christensen S, Pedersen R, Pereira M, Clausen T, Løppke C, Sand N, Ahrens T, Jørgensen A, Lim Y, Goksøyr L, Choudhary S, Gustavsson T, Dagil R, Daugaard M, Sander A, Torp M, Søgaard M, Theander T, Østrup O, Lassen U, Hamerlik P, Salanti A, Agerbæk M
Cells 2019;8(9):998

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Versican-Derived Matrikines Regulate Batf3–Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer

Hope C, Emmerich P, Papadas A, Pagenkopf A, Matkowskyj K, Van De Hey D, Payne S, Clipson L, Callander N, Hematti P, Miyamoto S, Johnson M, Deming D, Asimakopoulos F
The Journal of Immunology 2017;199(5):1933-1941

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Versican: a novel modulator of hepatic fibrosis

Bukong T, Maurice S, Chahal B, Schaeffer D, Winwood P
Laboratory Investigation 2016;96(3):361-374

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Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion.

Van Bockstal M, Lambein K, Van Gele M, De Vlieghere E, Limame R, Braems G, Van den Broecke R, Cocquyt V, Denys H, Bracke M, Libbrecht L, De Wever O
Oncoscience 2014;1(10):634-48

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Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion.

Van Bockstal M, Lambein K, Van Gele M, De Vlieghere E, Limame R, Braems G, Van den Broecke R, Cocquyt V, Denys H, Bracke M, Libbrecht L, De Wever O
Oncoscience 2014;1(10):634-48