Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-19051 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal E-Cadherin Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1.
Microporous scaffolds support assembly and differentiation of pancreatic progenitors into β-cell clusters.
Cadmium exposure upregulates SNAIL through miR-30 repression in human lung epithelial cells.
Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery.
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
AngII induces HepG2 cells to activate epithelial-mesenchymal transition.
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1.
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Size-dependent Effects of Gold Nanoparticles on Osteogenic Differentiation of Human Periodontal Ligament Progenitor Cells.
Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport.
E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer.
Glucocorticoid receptor-mediated delivery of nano gold-withaferin conjugates for reversal of epithelial-to-mesenchymal transition and tumor regression.
Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.
Downregulation of HMGA2 inhibits cellular proliferation and invasion, improves cellular apoptosis in prostate cancer.
Molecular mechanisms underlying human adipose tissue-derived stromal cells differentiation into a hepatocyte-like phenotype.
Chu JYS, Chau MKM, Chan CCY, Tai ACP, Cheung KF, Chan TM, Yung S
Molecular therapy. Nucleic acids 2019 Sep 6;17:78-91
Molecular therapy. Nucleic acids 2019 Sep 6;17:78-91
Microporous scaffolds support assembly and differentiation of pancreatic progenitors into β-cell clusters.
Youngblood RL, Sampson JP, Lebioda KR, Shea LD
Acta biomaterialia 2019 Sep 15;96:111-122
Acta biomaterialia 2019 Sep 15;96:111-122
Cadmium exposure upregulates SNAIL through miR-30 repression in human lung epithelial cells.
Tanwar VS, Zhang X, Jagannathan L, Jose CC, Cuddapah S
Toxicology and applied pharmacology 2019 Jun 15;373:1-9
Toxicology and applied pharmacology 2019 Jun 15;373:1-9
Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery.
Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, Zhao X, Lu C
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):62
Journal of experimental & clinical cancer research : CR 2019 Feb 8;38(1):62
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.
Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A
Cell metabolism 2019 Aug 6;30(2):385-401.e9
Cell metabolism 2019 Aug 6;30(2):385-401.e9
AngII induces HepG2 cells to activate epithelial-mesenchymal transition.
Qi M, Zhou Y, Liu J, Ou X, Li M, Long X, Ye J, Yu G
Experimental and therapeutic medicine 2018 Oct;16(4):3471-3477
Experimental and therapeutic medicine 2018 Oct;16(4):3471-3477
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1.
Jose CC, Jagannathan L, Tanwar VS, Zhang X, Zang C, Cuddapah S
Molecular carcinogenesis 2018 Jun;57(6):794-806
Molecular carcinogenesis 2018 Jun;57(6):794-806
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Chuang CH, Wang LY, Wong YM, Lin ES
Oncology letters 2018 Apr;15(4):4690-4696
Oncology letters 2018 Apr;15(4):4690-4696
Size-dependent Effects of Gold Nanoparticles on Osteogenic Differentiation of Human Periodontal Ligament Progenitor Cells.
Zhang Y, Kong N, Zhang Y, Yang W, Yan F
Theranostics 2017;7(5):1214-1224
Theranostics 2017;7(5):1214-1224
Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport.
Thamotharan S, Chu A, Kempf K, Janzen C, Grogan T, Elashoff DA, Devaskar SU
PloS one 2017;12(5):e0176493
PloS one 2017;12(5):e0176493
E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer.
Liao L, Song M, Li X, Tang L, Zhang T, Zhang L, Pan Y, Chouchane L, Ma X
Cancer research 2017 Apr 15;77(8):2090-2101
Cancer research 2017 Apr 15;77(8):2090-2101
Glucocorticoid receptor-mediated delivery of nano gold-withaferin conjugates for reversal of epithelial-to-mesenchymal transition and tumor regression.
Agarwalla P, Mukherjee S, Sreedhar B, Banerjee R
Nanomedicine (London, England) 2016 Oct;11(19):2529-46
Nanomedicine (London, England) 2016 Oct;11(19):2529-46
Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.
Mondal SK, Jinka S, Pal K, Nelli S, Dutta SK, Wang E, Ahmad A, AlKharfy KM, Mukhopadhyay D, Banerjee R
Molecular pharmaceutics 2016 Jul 5;13(7):2507-23
Molecular pharmaceutics 2016 Jul 5;13(7):2507-23
Downregulation of HMGA2 inhibits cellular proliferation and invasion, improves cellular apoptosis in prostate cancer.
Cai J, Shen G, Liu S, Meng Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):699-707
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):699-707
Molecular mechanisms underlying human adipose tissue-derived stromal cells differentiation into a hepatocyte-like phenotype.
Saulnier N, Piscaglia AC, Puglisi MA, Barba M, Arena V, Pani G, Alfieri S, Gasbarrini A
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2010 Dec;42(12):895-901
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2010 Dec;42(12):895-901
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: E-Cadherin Antibody (7H12) [NBP2-19051] - Analysis of E-Cadherin in LNCAP (1), A431 (2), DU145 (3), PC-3 (4), MCF-7 (5), PC-12 (6), NIH/3T3 (7), C6 (8) and COS7 (9) cell lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: E-Cadherin Antibody (7H12) [NBP2-19051] - IHC staining of E-Cadherin in gastric cancer tissues (left) and lung cancer tissues (right) with DAB staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: E-Cadherin Antibody (7H12) [NBP2-19051] - Human kidney distal tubules stained with E-CAD antibody. Secondary antibody: Donkey anti-Mouse Alexa Fluor 555. Imaging with a 40x objective from Zeiss Observer microscope with Apotome2. Image from verified customer review.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: E-Cadherin Antibody (7H12) [NBP2-19051] - Analysis of Hela cells using E-Cadherin mouse mAb (green) and negative control (purple).