Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- M00063-1 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-pan Cadherin 1 CDH1 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for E CADHERIN/CDH1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat E CADHERIN/CDH1 information: Molecular Weight: 97456 MW; Subcellular Localization: Cell junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma- catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane; Tissue Specificity: Non-neural epithelial tissues.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- COH-3
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Submitted references SNHG15-Mediated Localization of Nucleolin at the Cell Protrusions Regulates CDH2 mRNA Expression and Cell Invasion.
Hepatocyte-targeted delivery using oleanolic acid-loaded liposomes for enhanced hepatocellular carcinoma therapy.
A microfluidic lung-on-a-chip based on biomimetic hydrogel membrane.
Fabrication of sac-like hydrogel membranes for replicating curved tissue barriers on chips.
DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression.
Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells.
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Blocking 5-LO pathway alleviates renal fibrosis by inhibiting the epithelial-mesenchymal transition.
Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma.
Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress.
MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling.
Effect of grape seed proanthocyanidins on tumor vasculogenic mimicry in human triple-negative breast cancer cells.
MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7.
Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis.
Maintaining the pluripotency of mouse embryonic stem cells on gold nanoparticle layers with nanoscale but not microscale surface roughness.
Chen S, Zhou Y, Peng P, Xu L, Tang Q, Chen W, Gu W
International journal of molecular sciences 2023 Oct 26;24(21)
International journal of molecular sciences 2023 Oct 26;24(21)
Hepatocyte-targeted delivery using oleanolic acid-loaded liposomes for enhanced hepatocellular carcinoma therapy.
Wei X, Yang D, Xing Z, Cai J, Wang L, Zhao C, Wei X, Jiang M, Sun H, Zhou L, Fan Y, Nie H, Liu H
Biomaterials science 2023 May 30;11(11):3952-3964
Biomaterials science 2023 May 30;11(11):3952-3964
A microfluidic lung-on-a-chip based on biomimetic hydrogel membrane.
Shen C, Yang H, She W, Meng Q
Biotechnology and bioengineering 2023 Jul;120(7):2027-2038
Biotechnology and bioengineering 2023 Jul;120(7):2027-2038
Fabrication of sac-like hydrogel membranes for replicating curved tissue barriers on chips.
She W, Shen C, Ying Y, Meng Q
Lab on a chip 2023 Dec 20;24(1):85-96
Lab on a chip 2023 Dec 20;24(1):85-96
DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression.
Dong C, Huang S, Sun L, Yao J, Yan J, Yin X
Scientific reports 2022 Nov 17;12(1):19775
Scientific reports 2022 Nov 17;12(1):19775
Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells.
Wang R, Chen J, Yu H, Wei Z, Ma M, Ye X, Wu W, Chen H, Fu Z
Environmental toxicology 2022 May;37(5):1113-1123
Environmental toxicology 2022 May;37(5):1113-1123
Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer.
Bai X, Liu X, Li S, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Journal of agricultural and food chemistry 2022 Mar 30;70(12):3687-3696
Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer.
Bai X, Li S, Liu X, An H, Kang X, Guo S
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
Journal of agricultural and food chemistry 2022 Jul 13;70(27):8326-8337
Inhibition of TMEM16A by Natural Product Silibinin: Potential Lead Compounds for Treatment of Lung Adenocarcinoma.
Guo S, Bai X, Liu Y, Shi S, Wang X, Zhan Y, Kang X, Chen Y, An H
Frontiers in pharmacology 2021;12:643489
Frontiers in pharmacology 2021;12:643489
TMEM16A, a Homoharringtonine Receptor, as a Potential Endogenic Target for Lung Cancer Treatment.
Guo S, Bai X, Shi S, Deng Y, Kang X, An H
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
Blocking 5-LO pathway alleviates renal fibrosis by inhibiting the epithelial-mesenchymal transition.
Zhou J, Li R, Liu Q, Zhang J, Huang H, Huang C, Zhang G, Zhao Y, Wu T, Tang Q, Huang Y, Zhang Z, Li Y, He J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111470
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111470
Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma.
Dong L, Dong Q, Chen Y, Li Y, Zhang B, Zhou F, Lyu X, Chen GG, Lai P, Kung HF, He ML
Signal transduction and targeted therapy 2018;3:22
Signal transduction and targeted therapy 2018;3:22
Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress.
Zhao C, Lin M, Pan Y, Yu B
Gastroenterology research and practice 2018;2018:9252984
Gastroenterology research and practice 2018;2018:9252984
MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling.
Zhao Q, Xu L, Sun X, Zhang K, Shen H, Tian Y, Sun F, Li Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317707881
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317707881
Effect of grape seed proanthocyanidins on tumor vasculogenic mimicry in human triple-negative breast cancer cells.
Luan YY, Liu ZM, Zhong JY, Yao RY, Yu HS
Asian Pacific journal of cancer prevention : APJCP 2015;16(2):531-5
Asian Pacific journal of cancer prevention : APJCP 2015;16(2):531-5
MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7.
Deng B, Zhang Y, Zhang S, Wen F, Miao Y, Guo K
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(10):8065-73
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Sep;36(10):8065-73
Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
Duan F, Lin M, Li C, Ding X, Qian G, Zhang H, Ge S, Fan X, Li J
Cancer biology & therapy 2014 May;15(5):544-59
Cancer biology & therapy 2014 May;15(5):544-59
MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis.
Yang F, Zhou X, Miao X, Zhang T, Hang X, Tie R, Liu N, Tian F, Wang F, Yuan J
Breast cancer research and treatment 2014 May;145(1):23-32
Breast cancer research and treatment 2014 May;145(1):23-32
Maintaining the pluripotency of mouse embryonic stem cells on gold nanoparticle layers with nanoscale but not microscale surface roughness.
Lyu Z, Wang H, Wang Y, Ding K, Liu H, Yuan L, Shi X, Wang M, Wang Y, Chen H
Nanoscale 2014 Jun 21;6(12):6959-69
Nanoscale 2014 Jun 21;6(12):6959-69
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded colon cancer, using pan Cadherin Antibody .
- Additional image