10-7546-25

antibody from ABEOMICS Inc.

Targeting: CDH1 CD324, UVO, uvomorulin

Antibody data

Submit

Validation data

Product number: 10-7546-25 - Provider product page
Provider: ABEOMICS Inc.
Product name: Anti-E-cadherin Antibody
Antibody type: Monoclonal
Description: Epithelial cadherin (E-cadherin) is a calcium dependent cell-cell adhesion glycoprotein. It is associated with gland formation, stratification, and epithelial polarization. Its deregulation affects cell-cell adhesion and results in increased invasiveness of distinct human carcinomas like gastric cancer, malignancy, oral squamous cell carcinoma, Atypical parathyroid adenoma (APA). Loss of function of E-cadherin leads to the disappearance of epithelial characteristics of the cells and generates higher invasiveness for extracellular matrices. E-cadherin expression is considered to be a decisive indicator for differentiation, aggressive behaviour, high proliferation, metastasis, poor prognosis and invasiveness of human carcinoma cells.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: A partial length recombinant E-cadh erin protein (amino acids 438-556) was used as the immunogen for this antibody .
Isotype: IgG
Antibody clone number: ABM43F8
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing

CDH1 protein structure - 10-7546-25 shown in red.