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- Antibody Data
- Antigen structure
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- Product number
- Ab100725 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- E Cadherin Mouse mAb
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal (7H12) to E Cadherin, could be used for WB, IHC and Flow.Application WB: 1/500-1/2000 IHC: 1/200-1/1000Flow: 1/200-1/400ELISA: 1/10000PurityProtein G purified.Protein FunctionCadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 7H12
- Vial size
- 100_l,10_l,1ml,50_l
- Concentration
- 1 mg/ml
- Storage
- Storage: 4_; -20_ for long term storage. Avoid repeated freeze/thaw cycles.
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