Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L722 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-CEBPB monoclonal antibody, clone TD66-16
- Antibody type
- Monoclonal
- Description
- CCAAT-enhancer binding proteins (C/EBP) are basic region/leucine zipper (bZIP) transcription factors selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP ÉÇ is a member of the C/EBP transcription factor family. The C/EBP ÉÇ gene encodes several isoforms containing truncated transcription activation domains due to the alternative translational initiation at multipe AUG start sites. C/EBP ÉÇ is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein (LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP ÉÇ contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP ÉÇ gene that has direct implication for acute phase response in liver cells.The C/EBP ÉÇ form requires phosphorylation for its DNA binding ability, and increase binding of C/EBP ÉÇ isoforms during acute-phase reaction occurs through its upregulation and structural modification.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- TD66-16
- Vial size
- 100 _l
- Storage
- Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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