CABT-L722

antibody from Creative Diagnostics

Targeting: TNC DFNA56, HXB, MGC167029, TN

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-L722

Provider

Creative Diagnostics

Product name

Rabbit Anti-CEBPB monoclonal antibody, clone TD66-16

Antibody type

Monoclonal

Description

CCAAT-enhancer binding proteins (C/EBP) are basic region/leucine zipper (bZIP) transcription factors selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP ÉÇ is a member of the C/EBP transcription factor family. The C/EBP ÉÇ gene encodes several isoforms containing truncated transcription activation domains due to the alternative translational initiation at multipe AUG start sites. C/EBP ÉÇ is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein (LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP ÉÇ contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP ÉÇ gene that has direct implication for acute phase response in liver cells.The C/EBP ÉÇ form requires phosphorylation for its DNA binding ability, and increase binding of C/EBP ÉÇ isoforms during acute-phase reaction occurs through its upregulation and structural modification.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TD66-16

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.