67710-1-Ig

antibody from Proteintech Group

Targeting: TNC DFNA56, HXB, MGC167029, TN

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

67710-1-Ig

Provider

Proteintech Group

Product name

TNC/Tenascin-C antibody

Antibody type

Monoclonal

Description

TNC/Tenascin-C antibody (Cat. #67710-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1F7G8

Vial size

20ul, 150ul

References

Submitted references

IFITM1 is required for epithelial mesenchymal transition in airway remodeling of allergic asthma.

Zhu M, Weng X, Zhang C, Song X, Liu S, Xu T, Wang Z, Chen Z, Zhang M, Huang M, Ji N
The World Allergy Organization journal 2026 Mar;19(3):101339

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Tenascin C(+) myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice.

Tong X, Shi G, Fang Z, Tang S, Zhou B, Meng Q, Zhang P, Li H, Cai X, Wang Z, Zheng X, Chen W, Jiang G, Wang H, Jiang D, Li Q
Nature communications 2026 Jan 30;17(1)

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Celastrol disrupts the inflammatory feedback loop driven by Tenascin-C⁺ fibroblast subtype in psoriasis: Insights from single-cell RNA sequencing and experimental validation.

Ma Y, Zhang X, Chen X, Zhang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157988

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Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.

Hu ZQ, Ma R, Sun JQ, Peng M, Yuan J, Lai N, Liu J, Xia D
Journal of inflammation research 2025;18:3555-3570

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Piezoelectric Injectable Anti-Adhesive Hydrogel to Promote Endogenous Healing of Tendon Injuries.

Luo R, Xiong Y, Li J, Xiao M, Bai Y, Xu Z, Luo Z, Li C, Liang A, Feng H, Li Z
Advanced materials (Deerfield Beach, Fla.) 2025 Oct;37(40):e2501306

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Tenascin-C-enriched extracellular vesicles contribute to osteosarcoma progression via regulation of the angiotensin II receptor type 1 pathway.

Wang L, Liu K, Lyu L, Yin Z
Journal of molecular histology 2025 Nov 4;56(6):366

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A pharmacokinetic study of four bone-protective compounds after oral administration of WSZG extract in primary breast cancer mice.

Ning H, Huang Q, Wang J, Liu W, Wang J, Wang Y, Han X
Journal of pharmaceutical and biomedical analysis 2025 Nov 15;265:116996

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Shengmai Jianghuang San enhances radiosensitivity of hypoxic nasopharyngeal carcinoma by inhibiting cancer stemness.

Su C, Gong F, You Y, Jiang Z, Wen X, Wang Y, Lin S, Li F, Li J, Liu Y, Zhu D, Fan Q
QJM : monthly journal of the Association of Physicians 2025 Nov 1;118(11):817-829

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Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling.

Hao A, Dong X, Gou Y, Li A, Li J, Xiang H, Rahaman S, Zhu Y, Zhang H, You W, Shen G, Luo C, Mei O, Wu X, Shi LL, Reid RR, He TC, Fan J
Genes & diseases 2025 May;12(3):101484

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MicroRNA-9-5p regulates apoptosis of human osteoarthritis chondrocytes through suppressing TnC.

Yi X, Lei J, Hua Y, Chen C, Yang J
African health sciences 2025 Mar;25(1):179-192

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Critical Role for Transglutaminase 2 in Scleroderma Skin Fibrosis and in the Development of Dermal Sclerosis in a Mouse Model of Scleroderma.

Tam AYY, Khan K, Xu S, Bergin M, Huang L, Colon EA, Cheng D, Verderio EAM, Ong V, Denton CP, Atkinson J, Johnson TS, Abraham DJ
Arthritis & rheumatology (Hoboken, N.J.) 2025 Jul;77(7):914-928

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Topical Application of Nitrate Ameliorates Skin Fibrosis by Regulating ST2(+)CD4(+) T Cells in Systemic Sclerosis Mouse Model.

Gu J, Zhou Z, Xu S, Pan W, Wang J, Liu O, Wang S, Xu J
The Journal of investigative dermatology 2025 Feb;145(2):346-358.e5

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Role of integrin β1 and tenascin C mediate TGF-SMAD2/3 signaling in chondrogenic differentiation of BMSCs induced by type I collagen hydrogel.

Huang Y, Sun M, Lu Z, Zhong Q, Tan M, Wei Q, Zheng L
Regenerative biomaterials 2024;11:rbae017

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PMMA-induced biofilm promotes Schwann cells migration and proliferation mediated by EGF/Tnc/FN1 to improve sciatic nerve defect.

Wang J, Hu Y, Xue Y, Wang K, Mao D, Pan XY, Rui Y
Heliyon 2024 Sep 15;10(17):e37231

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NT-3 Combined with TGF-β Signaling Pathway Enhance the Repair of Spinal Cord Injury by Inhibiting Glial Scar Formation and Promoting Axonal Regeneration.

Chen T, He X, Wang J, Du D, Xu Y
Molecular biotechnology 2024 Jun;66(6):1484-1495

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Identification of diagnostic markers related to oxidative stress and inflammatory response in diabetic kidney disease by machine learning algorithms: Evidence from human transcriptomic data and mouse experiments.

Zhong M, Zhu E, Li N, Gong L, Xu H, Zhong Y, Gong K, Jiang S, Wang X, Fei L, Tang C, Lei Y, Wang Z, Zheng Z
Frontiers in endocrinology 2023;14:1134325

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3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy.

Li C, Wang J, Yang W, Yu K, Hong J, Ji X, Yao M, Li S, Lu J, Chen Y, Yan S, Wu H, Ma C, Yu X, Jiang G, Liu A
Journal of nanobiotechnology 2023 Jun 3;21(1):177

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Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.

Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99

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CEBPD is a master transcriptional factor for hypoxia regulated proteins in glioblastoma and augments hypoxia induced invasion through extracellular matrix-integrin mediated EGFR/PI3K pathway.

Mao XG, Xue XY, Lv R, Ji A, Shi TY, Chen XY, Jiang XF, Zhang X
Cell death & disease 2023 Apr 14;14(4):269

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Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.

Li X, Su Z, Shen K, Wang Q, Xu C, Wang F, Zhang Y, Jiang D
Oxidative medicine and cellular longevity 2022;2022:3945195