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- Antigen structure
- References [17]
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- Product number
- 21880-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21880-1-AP, RRID:AB_10836933
- Product name
- DSG2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DSG2 antibody (Cat. #21880-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Extracellular matrix mediates circulating tumor cell clustering in triple-negative breast cancer metastasis.
Two δ-catenins, plakophilin 4 and p120, promote formation of distinct types of adherens junctions.
Molecular mechanisms of ligustilide in the treatment of low endometrial receptivity: involvement of desmoglein-2.
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.
Actomyosin forces trigger a conformational change in desmoplakin within desmosomes.
Two δ-Catenins, Plakophilin 4 and p120, Promote Formation of Distinct Types of Adherens Junctions.
Desmoglein-2 was a novel cancer-associated fibroblasts-related biomarker for oral squamous cell carcinoma.
DSG2 and c-MYC Interact to Regulate the Expression of ADAM17 and Promote the Development of Cervical Cancer.
JNK inhibition enhances cell-cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes.
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
Plakophilin-3 Binds the Membrane and Filamentous Actin without Bundling F-Actin.
Inhibition of retinoid X receptor improved the morphology, localization of desmosomal proteins and paracellular permeability in three-dimensional cultures of mouse keratinocytes.
Plakophilin 3 and Par3 facilitate desmosomes' association with the apical junctional complex.
Desmoglein 2 (DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia.
O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.
Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.
Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.
Bobkov GO, Patel KJ, Lege BM, Zheng R, Shaulsky G, Ellis MJ, Cheng C
Nature communications 2026 Feb 6;17(1):1352
Nature communications 2026 Feb 6;17(1):1352
Two δ-catenins, plakophilin 4 and p120, promote formation of distinct types of adherens junctions.
Indra I, Troyanovsky RB, Korobova FV, Troyanovsky SM
The Journal of cell biology 2026 Apr 6;225(4)
The Journal of cell biology 2026 Apr 6;225(4)
Molecular mechanisms of ligustilide in the treatment of low endometrial receptivity: involvement of desmoglein-2.
He D, Ren X, Mao J, Shi S, Song Y, Xiao H, Wei A
Molecular human reproduction 2025 Oct 2;31(4)
Molecular human reproduction 2025 Oct 2;31(4)
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.
Ding Y, Zuo Y, Zhang B, Fan Y, Xu G, Cheng Z, Ma S, Fang S, Tian A, Gao D, Xu X, Wang Q, Jing Y, Jiang M, Xiong M, Li J, Han Z, Sun S, Wang S, He F, Yang J, Qu J, Zhang W, Liu GH
Cell 2025 Oct 2;188(20):5763-5784.e26
Cell 2025 Oct 2;188(20):5763-5784.e26
Actomyosin forces trigger a conformational change in desmoplakin within desmosomes.
Dong Y, Elgerbi A, Xie B, Han Y, Kwiatkowski AV, Choy JS, Sivasankar S
Nature communications 2025 Oct 10;16(1):9052
Nature communications 2025 Oct 10;16(1):9052
Two δ-Catenins, Plakophilin 4 and p120, Promote Formation of Distinct Types of Adherens Junctions.
Indra I, Troyanovsky RB, Korobova FV, Troyanovsky SM
bioRxiv : the preprint server for biology 2025 Jun 15;
bioRxiv : the preprint server for biology 2025 Jun 15;
Desmoglein-2 was a novel cancer-associated fibroblasts-related biomarker for oral squamous cell carcinoma.
Liu J, Sun Z, Cao S, Dai H, Zhang Z, Luo J, Wang X
BMC oral health 2025 Jan 20;25(1):102
BMC oral health 2025 Jan 20;25(1):102
DSG2 and c-MYC Interact to Regulate the Expression of ADAM17 and Promote the Development of Cervical Cancer.
Song LM, Yao DJ, Xia L, Wang XM, Liu T, Tang QQ, Zhou J
Cancer management and research 2024;16:703-710
Cancer management and research 2024;16:703-710
JNK inhibition enhances cell-cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes.
Ogawa S, Ishii T, Otani T, Inai Y, Matsuura T, Inai T
Histochemistry and cell biology 2024 Apr;161(4):345-357
Histochemistry and cell biology 2024 Apr;161(4):345-357
Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer.
Han JY, Che N, Mo J, Zhang DF, Liang XH, Dong XY, Zhao XL, Sun BC
BMC cancer 2024 Apr 26;24(1):532
BMC cancer 2024 Apr 26;24(1):532
Plakophilin-3 Binds the Membrane and Filamentous Actin without Bundling F-Actin.
Gupta J, Rangarajan ES, Troyanovsky RB, Indra I, Troyanovsky SM, Izard T
International journal of molecular sciences 2023 May 29;24(11)
International journal of molecular sciences 2023 May 29;24(11)
Inhibition of retinoid X receptor improved the morphology, localization of desmosomal proteins and paracellular permeability in three-dimensional cultures of mouse keratinocytes.
Ishikawa S, Nikaido M, Otani T, Ogata K, Iida H, Inai Y, Tamaoki S, Inai T
Microscopy (Oxford, England) 2022 Jun 6;71(3):152-160
Microscopy (Oxford, England) 2022 Jun 6;71(3):152-160
Plakophilin 3 and Par3 facilitate desmosomes' association with the apical junctional complex.
Indra I, Troyanovsky RB, Green KJ, Troyanovsky SM
Molecular biology of the cell 2021 Sep 1;32(19):1824-1837
Molecular biology of the cell 2021 Sep 1;32(19):1824-1837
Desmoglein 2 (DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia.
Zhang J, Ma K, Wang X, Jiang Y, Zhao S, Ou J, Lan W, Guan W, Wu X, Zheng H, Yang B, Wan C, Zhao W, Wu J, Zhang Q
Virologica Sinica 2021 Dec;36(6):1400-1410
Virologica Sinica 2021 Dec;36(6):1400-1410
O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.
Bagdonaite I, Pallesen EM, Ye Z, Vakhrushev SY, Marinova IN, Nielsen MI, Kramer SH, Pedersen SF, Joshi HJ, Bennett EP, Dabelsteen S, Wandall HH
EMBO reports 2020 Jun 4;21(6):e48885
EMBO reports 2020 Jun 4;21(6):e48885
Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.
Zhang J, Li Z, Qie M, Zheng R, Shetty J, Wang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2016 Aug;94:103-11
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2016 Aug;94:103-11
Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.
Zhang C, Zhang H, Yu L, Cao Y
Helicobacter 2014 Oct;19(5):330-42
Helicobacter 2014 Oct;19(5):330-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DSG2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human DSG2. This antibody recognizes human, mouse, rat antigen. The DSG2 antibody has been validated for the following applications: ELISA, WB analysis.
