Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 9271 - Provider product page
- Provider
- Cell Signaling Technology, Inc
- Proper citation
- Cell Signaling Technology Cat#9271, RRID:AB_329825
- Product name
- Phospho-Akt (Ser473) Antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Drosophila, Hamster, Porcine
- Host
- Rabbit
- Storage
- -20°C
Submitted references A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
SRC signaling is crucial in the growth of synovial sarcoma cells.
Temporal coding of insulin action through multiplexing of the AKT pathway.
Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbol esters.
Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively.
Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1.
Signaling networks assembled by oncogenic EGFR and c-Met.
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.
Phosphatidylinositol 3-kinase and Akt participate in the FSH-induced meiotic maturation of mouse oocytes.
PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects.
PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival.
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.
Controlled elimination of clathrin heavy-chain expression in DT40 lymphocytes.
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation.
CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice.
The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.
Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL
Nature cell biology 2013 Oct;15(10):1186-96
Nature cell biology 2013 Oct;15(10):1186-96
SRC signaling is crucial in the growth of synovial sarcoma cells.
Michels S, Trautmann M, Sievers E, Kindler D, Huss S, Renner M, Friedrichs N, Kirfel J, Steiner S, Endl E, Wurst P, Heukamp L, Penzel R, Larsson O, Kawai A, Tanaka S, Sonobe H, Schirmacher P, Mechtersheimer G, Wardelmann E, Büttner R, Hartmann W
Cancer research 2013 Apr 15;73(8):2518-28
Cancer research 2013 Apr 15;73(8):2518-28
Temporal coding of insulin action through multiplexing of the AKT pathway.
Kubota H, Noguchi R, Toyoshima Y, Ozaki Y, Uda S, Watanabe K, Ogawa W, Kuroda S
Molecular cell 2012 Jun 29;46(6):820-32
Molecular cell 2012 Jun 29;46(6):820-32
Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbol esters.
Fonseca BD, Alain T, Finestone LK, Huang BP, Rolfe M, Jiang T, Yao Z, Hernandez G, Bennett CF, Proud CG
The Journal of biological chemistry 2011 Aug 5;286(31):27111-22
The Journal of biological chemistry 2011 Aug 5;286(31):27111-22
Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively.
Chung YW, Kim HK, Kim IY, Yim MB, Chock PB
The Journal of biological chemistry 2011 Aug 26;286(34):29681-90
The Journal of biological chemistry 2011 Aug 26;286(34):29681-90
Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1.
Fukuhara S, Sako K, Minami T, Noda K, Kim HZ, Kodama T, Shibuya M, Takakura N, Koh GY, Mochizuki N
Nature cell biology 2008 May;10(5):513-26
Nature cell biology 2008 May;10(5):513-26
Signaling networks assembled by oncogenic EGFR and c-Met.
Guo A, Villén J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, Wang Y, MacNeill J, Mitchell J, Gygi SP, Rush J, Polakiewicz RD, Comb MJ
Proceedings of the National Academy of Sciences of the United States of America 2008 Jan 15;105(2):692-7
Proceedings of the National Academy of Sciences of the United States of America 2008 Jan 15;105(2):692-7
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK
Nature medicine 2008 Dec;14(12):1351-6
Nature medicine 2008 Dec;14(12):1351-6
Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.
Fujita H, Utsumi T, Muranaka S, Ogino T, Yano H, Akiyama J, Yasuda T, Utsumi K
Biochemical pharmacology 2005 Jun 15;69(12):1773-84
Biochemical pharmacology 2005 Jun 15;69(12):1773-84
Phosphatidylinositol 3-kinase and Akt participate in the FSH-induced meiotic maturation of mouse oocytes.
Hoshino Y, Yokoo M, Yoshida N, Sasada H, Matsumoto H, Sato E
Molecular reproduction and development 2004 Sep;69(1):77-86
Molecular reproduction and development 2004 Sep;69(1):77-86
PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects.
Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, Brancaccio M, Marengo S, Russo G, Azzolino O, Rybalkin SD, Silengo L, Altruda F, Wetzker R, Wymann MP, Lembo G, Hirsch E
Cell 2004 Aug 6;118(3):375-87
Cell 2004 Aug 6;118(3):375-87
PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival.
Fukuda T, Chen K, Shi X, Wu C
The Journal of biological chemistry 2003 Dec 19;278(51):51324-33
The Journal of biological chemistry 2003 Dec 19;278(51):51324-33
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.
Okkenhaug K, Bilancio A, Farjot G, Priddle H, Sancho S, Peskett E, Pearce W, Meek SE, Salpekar A, Waterfield MD, Smith AJ, Vanhaesebroeck B
Science (New York, N.Y.) 2002 Aug 9;297(5583):1031-4
Science (New York, N.Y.) 2002 Aug 9;297(5583):1031-4
Controlled elimination of clathrin heavy-chain expression in DT40 lymphocytes.
Wettey FR, Hawkins SF, Stewart A, Luzio JP, Howard JC, Jackson AP
Science (New York, N.Y.) 2002 Aug 30;297(5586):1521-5
Science (New York, N.Y.) 2002 Aug 30;297(5586):1521-5
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation.
Shan X, Czar MJ, Bunnell SC, Liu P, Liu Y, Schwartzberg PL, Wange RL
Molecular and cellular biology 2000 Sep;20(18):6945-57
Molecular and cellular biology 2000 Sep;20(18):6945-57
CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR
Nature 2000 Sep 14;407(6801):202-7
Nature 2000 Sep 14;407(6801):202-7
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice.
Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN
Nature genetics 2000 May;25(1):55-7
Nature genetics 2000 May;25(1):55-7
The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.
Sibilia M, Fleischmann A, Behrens A, Stingl L, Carroll J, Watt FM, Schlessinger J, Wagner EF
Cell 2000 Jul 21;102(2):211-20
Cell 2000 Jul 21;102(2):211-20
Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.
Tilton B, Ho L, Oberlin E, Loetscher P, Baleux F, Clark-Lewis I, Thelen M
The Journal of experimental medicine 2000 Aug 7;192(3):313-24
The Journal of experimental medicine 2000 Aug 7;192(3):313-24
No comments: Submit comment
No validations: Submit validation data