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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB18076 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18076, RRID:AB_10719919
- Product name
- AKT1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of AKT1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references High levels of phosphorylated form of Akt-1 in prostate cancer and non-neoplastic prostate tissues are strong predictors of biochemical recurrence.
Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae.
S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR).
Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation.
Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia.
Ayala G, Thompson T, Yang G, Frolov A, Li R, Scardino P, Ohori M, Wheeler T, Harper W
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Oct 1;10(19):6572-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Oct 1;10(19):6572-8
Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae.
Lungu AO, Jin ZG, Yamawaki H, Tanimoto T, Wong C, Berk BC
The Journal of biological chemistry 2004 Nov 19;279(47):48794-800
The Journal of biological chemistry 2004 Nov 19;279(47):48794-800
S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR).
Baudhuin LM, Jiang Y, Zaslavsky A, Ishii I, Chun J, Xu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Feb;18(2):341-3
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Feb;18(2):341-3
Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation.
Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, Hemmings BA
The Journal of biological chemistry 2004 Aug 20;279(34):35510-7
The Journal of biological chemistry 2004 Aug 20;279(34):35510-7
Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia.
Min YH, Cheong JW, Kim JY, Eom JI, Lee ST, Hahn JS, Ko YW, Lee MH
Cancer research 2004 Aug 1;64(15):5225-31
Cancer research 2004 Aug 1;64(15):5225-31
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from HeLa cells treated or untreated with heat shock using AKT1 polyclonal antibody (Cat # PAB18076).Peptide "+" means "with peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using AKT1 polyclonal antibody (Cat # PAB18076). Left : Untreated; Right: Treated with synthesized peptide.Peptide "+" means "with peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
