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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [21]
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- Product number
- ABIN361977 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN361977, RRID:AB_10955928
- Product name
- anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (pSer473) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer473 (Q-F-S (p) -Y-S) derived from Human Akt. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer473
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy.
Identification, design and bio-evaluation of novel Hsp90 inhibitors by ligand-based virtual screening.
5-Aza-2'-deoxycytidine inhibited PDGF-induced rat airway smooth muscle cell phenotypic switching.
MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN.
Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity.
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment.
Hydrogen sulfide postconditioning protects isolated rat hearts against ischemia and reperfusion injury mediated by the JAK2/STAT3 survival pathway.
Cannabinoid receptors CB1 and CB2 form functional heteromers in brain.
Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling.
WITHDRAWN: Glutamate Attenuates IGF-1 Receptor Signaling via NR2B containing NMDA Receptors 3 and neuronal Nitric Oxide Synthase.
Rb1 postconditioning attenuates liver warm ischemia-reperfusion injury through ROS-NO-HIF pathway.
Biotin ergopeptide probes for dopamine receptors.
The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model.
The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.
ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways.
Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes.
Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells.
Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
A cross-talk between oncogenic Ras and tumor suppressor PTEN through FAK Tyr861 phosphorylation in NIH/3T3 mouse embryonic fibroblasts.
A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts.
Shen J, Song G, An M, Li X, Wu N, Ruan K, Hu J, Hu R
Biomaterials 2014 Jan;35(1):316-26
Biomaterials 2014 Jan;35(1):316-26
Identification, design and bio-evaluation of novel Hsp90 inhibitors by ligand-based virtual screening.
Jia J, Xu X, Liu F, Guo X, Zhang M, Lu M, Xu L, Wei J, Zhu J, Zhang S, Zhang S, Sun H, You Q
PloS one 2013;8(4):e59315
PloS one 2013;8(4):e59315
5-Aza-2'-deoxycytidine inhibited PDGF-induced rat airway smooth muscle cell phenotypic switching.
Ning Y, Huang H, Dong Y, Sun Q, Zhang W, Xu W, Li Q
Archives of toxicology 2013 May;87(5):871-81
Archives of toxicology 2013 May;87(5):871-81
MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN.
Wang F, Li T, Zhang B, Li H, Wu Q, Yang L, Nie Y, Wu K, Shi Y, Fan D
Biochemical and biophysical research communications 2013 May 10;434(3):688-94
Biochemical and biophysical research communications 2013 May 10;434(3):688-94
Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity.
Zhang H, Hou J, Cui R, Guo X, Shi Z, Yang F, Dai J
Toxicology letters 2013 Mar 27;218(1):61-9
Toxicology letters 2013 Mar 27;218(1):61-9
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Ma L, Li J, Wang G, Gong S, Zhang L, Li K, Ji X, Liu Y, Chen P, Xiang X
Regulatory peptides 2013 Feb 10;181:9-16
Regulatory peptides 2013 Feb 10;181:9-16
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment.
Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV
Transfusion 2013 Dec;53(12):3164-73
Transfusion 2013 Dec;53(12):3164-73
Hydrogen sulfide postconditioning protects isolated rat hearts against ischemia and reperfusion injury mediated by the JAK2/STAT3 survival pathway.
Luan HF, Zhao ZB, Zhao QH, Zhu P, Xiu MY, Ji Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2012 Oct;45(10):898-905
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] 2012 Oct;45(10):898-905
Cannabinoid receptors CB1 and CB2 form functional heteromers in brain.
Callén L, Moreno E, Barroso-Chinea P, Moreno-Delgado D, Cortés A, Mallol J, Casadó V, Lanciego JL, Franco R, Lluis C, Canela EI, McCormick PJ
The Journal of biological chemistry 2012 Jun 15;287(25):20851-65
The Journal of biological chemistry 2012 Jun 15;287(25):20851-65
Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling.
Yu HC, Qin HY, He F, Wang L, Fu W, Liu D, Guo FC, Liang L, Dou KF, Han H
Hepatology (Baltimore, Md.) 2011 Sep 2;54(3):979-88
Hepatology (Baltimore, Md.) 2011 Sep 2;54(3):979-88
WITHDRAWN: Glutamate Attenuates IGF-1 Receptor Signaling via NR2B containing NMDA Receptors 3 and neuronal Nitric Oxide Synthase.
Han C, Quirion R, Zheng W
Biochemical and biophysical research communications 2011 Oct 6;
Biochemical and biophysical research communications 2011 Oct 6;
Rb1 postconditioning attenuates liver warm ischemia-reperfusion injury through ROS-NO-HIF pathway.
Guo Y, Yang T, Lu J, Li S, Wan L, Long D, Li Q, Feng L, Li Y
Life sciences 2011 Mar 28;88(13-14):598-605
Life sciences 2011 Mar 28;88(13-14):598-605
Biotin ergopeptide probes for dopamine receptors.
Vendrell M, Molero A, González S, Pérez-Capote K, Lluis C, McCormick PJ, Franco R, Cortés A, Casadó V, Albericio F, Royo M
Journal of medicinal chemistry 2011 Feb 24;54(4):1080-90
Journal of medicinal chemistry 2011 Feb 24;54(4):1080-90
The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model.
Ma H, Yao Q, Zhang AM, Lin S, Wang XX, Wu L, Sun JG, Chen ZT
Molecules (Basel, Switzerland) 2011 Dec 19;16(12):10556-69
Molecules (Basel, Switzerland) 2011 Dec 19;16(12):10556-69
The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice.
Li N, Liu GT
Acta pharmacologica Sinica 2010 Mar;31(3):265-72
Acta pharmacologica Sinica 2010 Mar;31(3):265-72
ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways.
Lin SL, Yan LY, Zhang XT, Yuan J, Li M, Qiao J, Wang ZY, Sun QY
PloS one 2010 Feb 2;5(2):e9013
PloS one 2010 Feb 2;5(2):e9013
Inhibition of uncoupling protein 2 by genipin reduces insulin-stimulated glucose uptake in 3T3-L1 adipocytes.
Zhou H, Zhao J, Zhang X
Archives of biochemistry and biophysics 2009 Jun 1;486(1):88-93
Archives of biochemistry and biophysics 2009 Jun 1;486(1):88-93
Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells.
Wang Z, Xu G, Wu Y, Guan Y, Cui L, Lei X, Zhang J, Mou L, Sun B, Dai Q
Medical & biological engineering & computing 2009 Jan;47(1):41-8
Medical & biological engineering & computing 2009 Jan;47(1):41-8
Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
Ren LN, Li QF, Xiao FJ, Yan J, Yang YF, Wang LS, Guo XZ, Wang H
Biochemical and biophysical research communications 2009 Aug 14;386(1):35-9
Biochemical and biophysical research communications 2009 Aug 14;386(1):35-9
A cross-talk between oncogenic Ras and tumor suppressor PTEN through FAK Tyr861 phosphorylation in NIH/3T3 mouse embryonic fibroblasts.
Bahk YY, Cho IH, Kim TS
Biochemical and biophysical research communications 2008 Dec 26;377(4):1199-204
Biochemical and biophysical research communications 2008 Dec 26;377(4):1199-204
A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts.
Kim S, Lee YZ, Kim YS, Bahk YY
Proteomics 2008 Aug;8(15):3082-93
Proteomics 2008 Aug;8(15):3082-93
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