ABIN362585

antibody from antibodies-online

Targeting: AKT1 AKT, PKB, PRKBA, RAC, RAC-alpha

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362585

Provider

antibodies-online

Product name

anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (AA 306-310) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 306-310 (M-K-T-F-C) derived from Human AKT1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Specificity/Sensitivity Akt (Ab-308) antibody detects endogenous levels of total Akt protein.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 306-310

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity.

Zhang H, Hou J, Cui R, Guo X, Shi Z, Yang F, Dai J
Toxicology letters 2013 Mar 27;218(1):61-9

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Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells.

Li N, Lu H, Chen C, Bu X, Huang P
Lipids in health and disease 2013 Jun 1;12:83

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The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells.

Li N, Bu X, Wu P, Wu P, Huang P
Lipids 2012 Apr;47(4):403-11

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Rb1 postconditioning attenuates liver warm ischemia-reperfusion injury through ROS-NO-HIF pathway.

Guo Y, Yang T, Lu J, Li S, Wan L, Long D, Li Q, Feng L, Li Y
Life sciences 2011 Mar 28;88(13-14):598-605

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Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors: Different profiles of AAL993 versus SU5416 and KRN633.

Ban HS, Uno M, Nakamura H
Cancer letters 2010 Oct 1;296(1):17-26

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Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.

Tremblay F, Krebs M, Dombrowski L, Brehm A, Bernroider E, Roth E, Nowotny P, Waldhäusl W, Marette A, Roden M
Diabetes 2005 Sep;54(9):2674-84

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WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism.

Xu BE, Stippec S, Lazrak A, Huang CL, Cobb MH
The Journal of biological chemistry 2005 Oct 7;280(40):34218-23

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Mutant PIK3CA promotes cell growth and invasion of human cancer cells.

Samuels Y, Diaz LA Jr, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE
Cancer cell 2005 Jun;7(6):561-73

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Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M
Cell death and differentiation 2005 Jun;12(6):668-77