ABIN358371

antibody from antibodies-online

Targeting: AKT1 AKT, PKB, PRKBA, RAC, RAC-alpha

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN358371

Provider

antibodies-online

Product name

anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (pSer473) antibody

Antibody type

Polyclonal

Antigen

This antibody is generated from rabbits immunized with a KLH conjugated syntheticphosphopeptide corresponding to amino acid residues surrounding S473 of human AKT1.

Reactivity

Human

Host

Rabbit

Vial size

0.1 mg

Concentration

0.25 mg/ml

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

References

Submitted references

Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis.

Liao Y, Hung MC
Molecular and cellular biology 2003 Oct;23(19):6836-48

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Reciprocal regulation of MelCAM and AKT in human melanoma.

Li G, Kalabis J, Xu X, Meier F, Oka M, Bogenrieder T, Herlyn M
Oncogene 2003 Oct 9;22(44):6891-9

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Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner.

Debnath J, Walker SJ, Brugge JS
The Journal of cell biology 2003 Oct 27;163(2):315-26

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Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

Powell DJ, Hajduch E, Kular G, Hundal HS
Molecular and cellular biology 2003 Nov;23(21):7794-808

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Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer.

Liao Y, Grobholz R, Abel U, Trojan L, Michel MS, Angel P, Mayer D
International journal of cancer. Journal international du cancer 2003 Nov 20;107(4):676-80