ABIN117899

antibody from antibodies-online

Targeting: AKT1 AKT, PKB, PRKBA, RAC, RAC-alpha

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN117899

Provider

antibodies-online

Product name

anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (pThr308) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to aa 302-311 of Human AKT protein conjugated to KLHAA Sequence: DGATMK(p)TFCG

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

0.1 mg

Concentration

0.97 mg/ml (by UV absorbance at 280 nm)

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

References

Submitted references

Akt1 contains a functional leucine-rich nuclear export sequence.

Saji M, Vasko V, Kada F, Allbritton EH, Burman KD, Ringel MD
Biochemical and biophysical research communications 2005 Jun 24;332(1):167-73

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Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.

Sutherland BW, Kucab J, Wu J, Lee C, Cheang MC, Yorida E, Turbin D, Dedhar S, Nelson C, Pollak M, Leighton Grimes H, Miller K, Badve S, Huntsman D, Blake-Gilks C, Chen M, Pallen CJ, Dunn SE
Oncogene 2005 Jun 16;24(26):4281-92

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PKB mediates c-erbB2-induced epithelial beta1 integrin conformational inactivation through Rho-independent F-actin rearrangements.

Hedjazifar S, Jenndahl LE, Shimokawa H, Baeckström D
Experimental cell research 2005 Jul 1;307(1):259-75

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Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture.

Alessi DR
Biochemical Society transactions 2001 May;29(Pt 2):1-14

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PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

Lawlor MA, Alessi DR
Journal of cell science 2001 Aug;114(Pt 16):2903-10