ABIN196709

antibody from antibodies-online

Targeting: AKT1 AKT, PKB, PRKBA, RAC, RAC-alpha

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN196709

Provider

antibodies-online

Product name

anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (pSer473) antibody

Antibody type

Polyclonal

Description

Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer473

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR).

Baudhuin LM, Jiang Y, Zaslavsky A, Ishii I, Chun J, Xu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Feb;18(2):341-3

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Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation.

Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, Hemmings BA
The Journal of biological chemistry 2004 Aug 20;279(34):35510-7

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Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia.

Min YH, Cheong JW, Kim JY, Eom JI, Lee ST, Hahn JS, Ko YW, Lee MH
Cancer research 2004 Aug 1;64(15):5225-31