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- References [11]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 18148-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18148-1-AP, RRID:AB_2241281
- Product name
- UBE4B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UBE4B antibody (Cat. #18148-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Nuclear IL-33-driven UBE4B expression tilts human macrophages toward the M2 phenotype via p53 ubiquitination.
UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma.
UBE4B promotes gastric cancer proliferation and metastasis by mediating FAT4 ubiquitination and degradation.
UBE4B-driven suppression of megakaryocyte maturation by HBV: A novel mechanism linking viral infection to thrombocytopenia via p53-ERK1/2 crosstalk.
UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage.
E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response.
UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling.
The Roles of Ubiquitination Factor E4B (UBE4B) in the Postoperative Prognosis of Patients with Renal Cell Carcinoma and in Renal Tumor Cells Growth and Metastasis.
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma.
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Ren S, Liu R, Yu Y, Liu L, Luo H, Xu J, Xie Y, Sun H, Zhang W, Li D
Biochimica et biophysica acta. Molecular cell research 2026 Apr 3;1873(5):120144
Biochimica et biophysica acta. Molecular cell research 2026 Apr 3;1873(5):120144
UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma.
Wang L, Huan XJ, Song SS, Bao XB, Tian CQ, Miao ZH, Wang YQ
Biochemical pharmacology 2025 Jul;237:116943
Biochemical pharmacology 2025 Jul;237:116943
UBE4B promotes gastric cancer proliferation and metastasis by mediating FAT4 ubiquitination and degradation.
Wu K, Guo Z, Fu Y, Yang S, Pan Y, Yan R, Zhou X
Cell death & disease 2025 Jul 23;16(1):551
Cell death & disease 2025 Jul 23;16(1):551
UBE4B-driven suppression of megakaryocyte maturation by HBV: A novel mechanism linking viral infection to thrombocytopenia via p53-ERK1/2 crosstalk.
Jiang H, Li Y, Dou X, Han C, Fan Y
Cellular signalling 2025 Dec;136:112089
Cellular signalling 2025 Dec;136:112089
UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage.
Hu X, Zou R, Zhang Z, Ji J, Li J, Huo XY, Liu D, Ge MX, Cui MK, Wu MZ, Li ZP, Wang Q, Zhang X, Zhang ZR
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Jun;1866(2):194937
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Jun;1866(2):194937
E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response.
Anton V, Buntenbroich I, Simões T, Joaquim M, Müller L, Buettner R, Odenthal M, Hoppe T, Escobar-Henriques M
Molecular cell 2023 Aug 17;83(16):2976-2990.e9
Molecular cell 2023 Aug 17;83(16):2976-2990.e9
UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling.
Wu S, Xie L, Cheng S, Fan Z, Sang H, Li Q
Pathology, research and practice 2022 Apr;232:153762
Pathology, research and practice 2022 Apr;232:153762
The Roles of Ubiquitination Factor E4B (UBE4B) in the Postoperative Prognosis of Patients with Renal Cell Carcinoma and in Renal Tumor Cells Growth and Metastasis.
Huang XQ, Hao S, Zhou ZQ, Huang B, Fang JY, Tang Y, Zhang JH, Xia JC
OncoTargets and therapy 2020;13:185-197
OncoTargets and therapy 2020;13:185-197
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9
Molecular cell 2020 Jul 16;79(2):320-331.e9
Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma.
Zhang XF, Pan QZ, Pan K, Weng DS, Wang QJ, Zhao JJ, He J, Liu Q, Wang DD, Jiang SS, Zheng HX, Lv L, Chen CL, Zhang HX, Xia JC
Molecular carcinogenesis 2016 Jan;55(1):64-76
Molecular carcinogenesis 2016 Jan;55(1):64-76
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Zhang H, Wu P, Chen F, Hao Y, Lao Y, Ren L, Sun L, Sun W, Wei H, Chan DW, Jiang Y, He F
Proteomics 2014 Sep;14(17-18):1977-86
Proteomics 2014 Sep;14(17-18):1977-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 18148-1-AP( UBE4B Antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UBE4B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human UBE4B. This antibody recognizes human,mouse,rat antigen. The UBE4B antibody has been validated for the following applications: ELISA, IF, IHC, WB analysis.
