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- References [21]
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- Immunohistochemistry [1]
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- Product number
- 13105-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13105-1-AP, RRID:AB_2265336
- Product name
- KIF2A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIF2A antibody (Cat. #13105-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, Canine and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references KIF2A-mediated microtubule-dependent nuclear envelope invagination drives nonhomologous end joining.
The mechanisms of MTOCs maturation in human and mouse oocytes.
Proximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins.
APC orchestrates microtubule dynamics by acting as a positive regulator of KIF2A and a negative regulator of CLASPs.
Psrc1 Ensures Proper Spindle Assembly and Chromosome Segregation During Mouse Oocyte Maturation.
Novel Diaryl-Substituted Pyrazolo[3,4-d]pyrimidines as Tubulin/CDC5L Dual-Targeting Ligands: Discovery, Potent Antitumor Activity, and Good Metabolic Stability.
Targeting S100A8/A9-NCF1 axis in tumor microenvironment to prevent tumor metastasis by self-assembled peptide nanofibers.
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
CtIP regulates G2/M transition and bipolar spindle assembly during mouse oocyte meiosis.
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5.
Mcrs1 regulates G2/M transition and spindle assembly during mouse oocyte meiosis.
Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.
The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network.
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.
Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons.
The mechanism of acentrosomal spindle assembly in human oocytes.
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin.
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment.
High KIF2A expression promotes proliferation, migration and predicts poor prognosis in lung adenocarcinoma.
Ma Y, Zhang T, Zhou XA, Xu Z, Zhou J, Aili A, Li P, Nie C, Xiong Y, Li X, Cao B, Li S, Wang J
Nucleic acids research 2026 Jan 22;54(3)
Nucleic acids research 2026 Jan 22;54(3)
The mechanisms of MTOCs maturation in human and mouse oocytes.
Gu H, Wu L, Yin M, Du X, Fu J, Xu F, Ye Z, Zhang X, Jing H, Luo Y, Li W, Sun X, He L, Kuang Y, Lyu Q, Wu T, Wang L, Sang Q
Science bulletin 2025 Oct 15;70(19):3202-3214
Science bulletin 2025 Oct 15;70(19):3202-3214
Proximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins.
Yoshioka K, Nakagawa R, Nguyen CLK, Suzuki H, Ishigaki K, Mizuno S, Okiyoneda T, Ebihara S, Murata K
FEBS open bio 2025 Jan;15(1):151-164
FEBS open bio 2025 Jan;15(1):151-164
APC orchestrates microtubule dynamics by acting as a positive regulator of KIF2A and a negative regulator of CLASPs.
Wang Y, Liu X, Liu Z, Hua S, Jiang K
Cell insight 2025 Feb;4(1):100210
Cell insight 2025 Feb;4(1):100210
Psrc1 Ensures Proper Spindle Assembly and Chromosome Segregation During Mouse Oocyte Maturation.
Xin-Jie W, Kang-Na W, Yu-Qing L, Zhao-Cheng Z, Hui-Sheng L, Jiang J, Li-Xin Z, Hai-Long W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70928
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70928
Novel Diaryl-Substituted Pyrazolo[3,4-d]pyrimidines as Tubulin/CDC5L Dual-Targeting Ligands: Discovery, Potent Antitumor Activity, and Good Metabolic Stability.
Shi Z, Wang R, Mo H, Chen J, Li S, Gao F, Liang Y, Zhang J, Wang Y
Journal of medicinal chemistry 2025 Aug 28;68(16):17258-17286
Journal of medicinal chemistry 2025 Aug 28;68(16):17258-17286
Targeting S100A8/A9-NCF1 axis in tumor microenvironment to prevent tumor metastasis by self-assembled peptide nanofibers.
Guo Y, Zhang Z, Huang H, Wu Y, Yin L, Zhou Y, Ding F, Hong S, Steinmetz NF, Cai H
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1502-1518
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Apr 2;33(4):1502-1518
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Zhang X, Guo J, Shi X, Zhou X, Chen Q
Cell insight 2024 Jun;3(3):100170
Cell insight 2024 Jun;3(3):100170
CtIP regulates G2/M transition and bipolar spindle assembly during mouse oocyte meiosis.
Yue W, Zhang HY, Schatten H, Meng TG, Sun QY
Journal of genetics and genomics = Yi chuan xue bao 2024 Dec;51(12):1435-1446
Journal of genetics and genomics = Yi chuan xue bao 2024 Dec;51(12):1435-1446
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5.
Chen Y, Su H, Zhao J, Na Z, Jiang K, Bacchiocchi A, Loh KH, Halaban R, Wang Z, Cao X, Slavoff SA
Cell reports 2023 Sep 26;42(9):113145
Cell reports 2023 Sep 26;42(9):113145
Mcrs1 regulates G2/M transition and spindle assembly during mouse oocyte meiosis.
Ju JQ, Pan ZN, Zhang KH, Ji YM, Liu JC, Sun SC
EMBO reports 2023 May 4;24(5):e56273
EMBO reports 2023 May 4;24(5):e56273
Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling.
Yuan G, Yang ST, Yang S
Molecular therapy. Nucleic acids 2023 Mar 14;31:197-210
Molecular therapy. Nucleic acids 2023 Mar 14;31:197-210
The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network.
Guan C, Hua S, Jiang K
The EMBO journal 2023 Jun 1;42(11):e112953
The EMBO journal 2023 Jun 1;42(11):e112953
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.
Yuan G, Yang S, Yang S
International journal of oral science 2023 Feb 16;15(1):11
International journal of oral science 2023 Feb 16;15(1):11
Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons.
Ruiz-Reig N, García-Sánchez D, Schakman O, Gailly P, Tissir F
Frontiers in molecular neuroscience 2022;15:1110986
Frontiers in molecular neuroscience 2022;15:1110986
The mechanism of acentrosomal spindle assembly in human oocytes.
Wu T, Dong J, Fu J, Kuang Y, Chen B, Gu H, Luo Y, Gu R, Zhang M, Li W, Dong X, Sun X, Sang Q, Wang L
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabq7361
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabq7361
Identification of Glycolysis-Related lncRNAs and the Novel lncRNA WAC-AS1 Promotes Glycolysis and Tumor Progression in Hepatocellular Carcinoma.
Xia X, Zhang H, Xia P, Zhu Y, Liu J, Xu K, Yuan Y
Frontiers in oncology 2021;11:733595
Frontiers in oncology 2021;11:733595
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin.
Huang J, Liang Z, Guan C, Hua S, Jiang K
The Journal of cell biology 2021 Aug 2;220(8)
The Journal of cell biology 2021 Aug 2;220(8)
KIF2A promotes the progression via AKT signaling pathway and is upregulated by transcription factor ETV4 in human gastric cancer.
Zhang X, Wang Y, Liu X, Zhao A, Yang Z, Kong F, Sun L, Yu Y, Jiang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109840
Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment.
Yang H, Zhang F, Huang CJ, Liao J, Han Y, Hao P, Chu Y, Lu X, Li W, Yu H, Kang J
Molecular biology of the cell 2019 Apr 15;30(9):1060-1068
Molecular biology of the cell 2019 Apr 15;30(9):1060-1068
High KIF2A expression promotes proliferation, migration and predicts poor prognosis in lung adenocarcinoma.
Xie T, Li X, Ye F, Lu C, Huang H, Wang F, Cao X, Zhong C
Biochemical and biophysical research communications 2018 Feb 26;497(1):65-72
Biochemical and biophysical research communications 2018 Feb 26;497(1):65-72
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13105-1-AP( KIF2A Antibody) at dilution of 1:1200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIF2A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KIF2A. This antibody recognizes human,mouse,rat antigen. The KIF2A antibody has been validated for the following applications: ELISA, IHC, WB analysis.
