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- References [14]
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- Immunohistochemistry [1]
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- Product number
- 13128-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13128-1-AP, RRID:AB_2294094
- Product name
- FDFT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FDFT1 antibody (Cat. #13128-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of FDA-approved drugs that increase mevalonate kinase in hyper IgD syndrome.
Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer.
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer.
Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression.
Hibiscus syriacus L. cultivated in callus culture exerts cytotoxicity in colorectal cancer via Notch signaling-mediated cholesterol biosynthesis suppression.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer.
20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition.
Politiek FA, Turkenburg M, Koster J, Ofman R, Waterham HR
Journal of inherited metabolic disease 2024 Mar;47(2):302-316
Journal of inherited metabolic disease 2024 Mar;47(2):302-316
Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.
Tran GB, Ding J, Ye B, Liu M, Yu Y, Zha Y, Dong Z, Liu K, Sudarshan S, Ding HF
Cancer research 2023 Jul 5;83(13):2248-2261
Cancer research 2023 Jul 5;83(13):2248-2261
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Cell death & disease 2023 Aug 4;14(8):497
Cell death & disease 2023 Aug 4;14(8):497
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer.
Zheng YK, Zhou ZS, Wang GZ, Tu JY, Cheng HB, Ma SZ, Ke C, Wang Y, Jian QP, Shu YH, Wu XW
Cell death & disease 2023 Apr 1;14(4):234
Cell death & disease 2023 Apr 1;14(4):234
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.
Li JQ, Jiang HJ, Su XY, Feng L, Zhan NZ, Li SS, Chen ZJ, Chang BH, Cheng PZ, Yang L, Pei GX
Stem cells international 2022;2022:4363632
Stem cells international 2022;2022:4363632
Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC.
Huang R, Zhang C, Wang X, Zou X, Xiang Z, Wang Z, Gui B, Lin T, Hu H
Cancer medicine 2022 Nov;11(21):3993-4004
Cancer medicine 2022 Nov;11(21):3993-4004
Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer.
Guo C, Wan R, He Y, Lin SH, Cao J, Qiu Y, Zhang T, Zhao Q, Niu Y, Jin Y, Huang HY, Wang X, Tan L, Thomas RK, Zhang H, Chen L, Wong KK, Hu L, Ji H
Nature cancer 2022 May;3(5):614-628
Nature cancer 2022 May;3(5):614-628
Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression.
Jiang H, Tang E, Chen Y, Liu H, Zhao Y, Lin M, He L
Cancer science 2022 Mar;113(3):971-985
Cancer science 2022 Mar;113(3):971-985
Hibiscus syriacus L. cultivated in callus culture exerts cytotoxicity in colorectal cancer via Notch signaling-mediated cholesterol biosynthesis suppression.
Xu XY, Choi HS, Park SY, Kim JK, Seo KH, Kim H, Kim YJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153870
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153870
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer.
Biancur DE, Kapner KS, Yamamoto K, Banh RS, Neggers JE, Sohn ASW, Wu W, Manguso RT, Brown A, Root DE, Aguirre AJ, Kimmelman AC
Cell metabolism 2021 Jan 5;33(1):199-210.e8
Cell metabolism 2021 Jan 5;33(1):199-210.e8
20(S)-Rg3 upregulates FDFT1 via reducing miR-4425 to inhibit ovarian cancer progression.
Lu J, Zhou Y, Zheng X, Chen L, Tuo X, Chen H, Xue M, Chen Q, Chen W, Li X, Zhao L
Archives of biochemistry and biophysics 2020 Oct 30;693:108569
Archives of biochemistry and biophysics 2020 Oct 30;693:108569
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484
Nature 2020 Dec;588(7838):479-484
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition.
Mahoney CE, Pirman D, Chubukov V, Sleger T, Hayes S, Fan ZP, Allen EL, Chen Y, Huang L, Liu M, Zhang Y, McDonald G, Narayanaswamy R, Choe S, Chen Y, Gross S, Cianchetta G, Padyana AK, Murray S, Liu W, Marks KM, Murtie J, Dorsch M, Jin S, Nagaraja N, Biller SA, Roddy T, Popovici-Muller J, Smolen GA
Nature communications 2019 Jan 9;10(1):96
Nature communications 2019 Jan 9;10(1):96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 13128-1-AP(SQS antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SQS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SQS. This antibody recognizes human, mouse, rat antigen. The SQS antibody has been validated for the following applications: ELISA, WB, IHC analysis.
