66822-1-Ig

antibody from Proteintech Group

Targeting: USP4 UNP, Unph

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66822-1-Ig

Provider

Proteintech Group

Product name

USP4 antibody

Antibody type

Monoclonal

Description

USP4 antibody (Cat. #66822-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1G11G8

Vial size

20ul, 150ul

References

Submitted references

Melatonin-engineered MSCs-exosomes deliver USP4 to stabilise ARNTL and inhibit clock rhythmic ferroptosis for enhanced flap survival.

Jiang X, Wang Y, Zhang X, Deng H, Fang L, Tafadzwa C, Yao J, Chen H, Ye A, Zhou K, Ling X, Xiao J
Clinical and translational medicine 2026 Jan;16(1):e70565

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IL27RA promotes the proliferation and metastasis of hepatocellular carcinoma cells by regulating TGFβR1.

Zhang Y, Wu Y, Zhang Q, Xiong J, Xiao B, Zuo S
Scientific reports 2025 Oct 30;15(1):37959

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USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer.

Xie Z, Lin H, Wu Y, Yu Y, Liu X, Zheng Y, Wang X, Wu J, Xu M, Han Y, Zhang Q, Deng Y, Lin L, Linzhu Y, Qingyun L, Lin X, Huang Y, Chi P
Cell death & disease 2025 Feb 8;16(1):81

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USP4 depletion-driven RAB7A ubiquitylation impairs autophagosome-lysosome fusion and aggravates periodontitis.

Kang S, Liu S, Dong X, Li H, Qian Y, Dai A, He W, Li X, Chen Q, Wang H, Ding PH
Autophagy 2025 Apr;21(4):771-788

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The deubiquitinating enzyme USP4 regulates BRCA1 stability and function.

Guo X, Ma Y, Zhang T, Liu R, Chang F, Yan X, Yu T, Wu P, Li Q, Xu L, Duan J, Li L, Su Y, Shao G
NPJ breast cancer 2024 May 11;10(1):35

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The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice.

Horan TS, Ascenção CFR, Mellor C, Wang M, Smolka MB, Cohen PE
PLoS genetics 2024 Feb;20(2):e1011175

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Vialinin A alleviates oxidative stress and neuronal injuries after ischaemic stroke by accelerating Keap1 degradation through inhibiting USP4-mediated deubiquitination.

Mao M, Xia Q, Zhan G, Bing H, Zhang C, Wang J, Tian W, Lian H, Li X, Chu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155304

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USP4 promotes the proliferation and glucose metabolism of gastric cancer cells by upregulating PKM2.

Chen Y, Guo Y, Yuan M, Guo S, Cui S, Chen D
PloS one 2023;18(8):e0290688

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The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice.

Horan TS, Ascenção CFR, Mellor CA, Wang M, Smolka MB, Cohen PE
bioRxiv : the preprint server for biology 2023 Oct 8;

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USP4 promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting TAK1.

Zhang H, Han Y, Xiao W, Gao Y, Sui Z, Ren P, Meng F, Tang P, Yu Z
Cell death & disease 2023 Nov 10;14(11):730

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Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin.

Guo Y, Tian J, Guo Y, Wang C, Chen C, Cai S, Yu W, Sun B, Yan J, Li Z, Fan J, Qi Q, Zhang D, Jin W, Hua Z, Chen G
Cell reports 2023 Dec 26;42(12):113511