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LearnBS61323
antibody from Bioworld Technology, Inc
Targeting: IL27RA
CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Western blot [1]
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- Product number
- BS61323 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- IL27RA polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human IL27RA.
- Description
- IL-27 is a heterodimeric cytokine that consists of EBI3, an IL-12p40-related protein, and p28, a IL-12p35-related polypeptide. IL-27 triggers expansion of antigen-specific naive CD4-positive T cells and promotes polarization towards a Th1 phenotype with expression of gamma-interferon. IL-27 contributes to the development of an adaptive immune response through its action on CD4-positive T cells, and also directly acts on cells of the innate immune system. IL-27 protein levels increase upon activation of antigen-presenting cells. IL-27 protein induces orphan cytokine receptor IL-27R (WSX-1)-dependent clonal expansion of naive but not memory CD4(+) T cells. IL-27 signaling through IL-27R and gp130 also induces phosphorylation of Stat1-5.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -27°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of IL27RA pAb at 1:500 dilutionLine1:HEPG2 whole cell lysateLine2:Raw264.7 whole cell lysateLine3:The Liver tissue lysate of Rat
