Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- AF1479 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-27 R alpha/WSX-1/TCCR Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-27 R alpha/WSX-1/TCCR in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse TCCR is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q6UWB1
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references A soluble form of IL-27Rα is a natural IL-27 antagonist.
IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.
Dietrich C, Candon S, Ruemmele FM, Devergne O
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 1;192(11):5382-9
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 1;192(11):5382-9
IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.
Furukawa M, Takaishi H, Takito J, Yoda M, Sakai S, Hikata T, Hakozaki A, Uchikawa S, Matsumoto M, Chiba K, Kimura T, Okada Y, Matsuo K, Yoshida H, Toyama Y
Journal of immunology (Baltimore, Md. : 1950) 2009 Aug 15;183(4):2397-406
Journal of immunology (Baltimore, Md. : 1950) 2009 Aug 15;183(4):2397-406
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