Antibody data
- Antibody Data
- Antigen structure
- References [54]
- Comments [0]
- Validations [0]
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- Product number
- 23498-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- Laminin beta 1 antibody
- Antibody type
- Polyclonal
- Description
- Laminin beta 1 antibody (Cat. #23498-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction.
TREM2 Facilitates Myelin Debris Clearance but Exacerbates Chronic Inflammation and Fibrosis After Spinal Cord Injury.
f-SPION-mediated magnetic stimulation induces reparative Schwann cell reprogramming via cytoskeletal dynamics - gated activation of Piezo1.
Neonatal Spinal-Cord-Like Scaffold with Hierarchical Structural and Neurogenetic Microenvironments for Spinal Cord Injury Repair.
Injectable Brain Extracellular Matrix Hydrogels Enhance Neuronal Migration and Functional Recovery After Intracerebral Hemorrhage.
Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth.
SIRT5 induces glomerular sclerosis in diabetic nephropathy through p53.
Interplay of axon regeneration genes and immune infiltration in spinal cord injury.
Jianpi Qiangji Granule ameliorates aging-associated sarcopenia via AMPK/PGC-1α axis in SAMP8 mice.
Neuromuscular electrical stimulation alleviates stroke-related sarcopenia by promoting satellite cells myogenic differentiation via AMPK-ULK1-Autophagy axis.
Lnc-DARVR/miR-365-1-5p/LAMB1 axis regulates rotavirus replication via the complement C3 pathway.
Functional analysis of pathogenic variants in LAMB1-related leukoencephalopathy reveals genotype-phenotype correlations and suggests its role in glial cells.
LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment.
Mesenchymal stem cell-specific Sirt1 overexpression prevents sarcopenia induced by 1,25-dihydroxyvitamin D deficiency.
E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair.
Identification and Validation of Basement Membrane Related LncRNA Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma.
Bushen Tongluo recipe improves oxidative stress homeostasis, inhibits transforming growth factor/Notch signaling pathway, and regulates the lncRNA maternally expressed gene 3/miR-145 axis to delay diabetic kidney disease.
FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis.
Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages.
Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.
Recombinant Humanized Collagen Enhances Secreted Protein Levels of Fibroblasts and Facilitates Rats' Skin Basement Membrane Reinforcement.
Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.
Galectin-3 inhibition reduces fibrotic scarring and promotes functional recovery after spinal cord injury in mice.
A proteomics-based study of the mechanism of oxymatrine to ameliorate hepatic fibrosis in mice.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear.
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells.
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
3D artificial sebocyte glands from inertial focusing effect for facile and flexible analysis of light damage and drug screening.
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway.
Cytosolic p53 Inhibits Parkin-Mediated Mitophagy and Promotes Acute Liver Injury Induced by Heat Stroke.
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4.
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Stub1 maintains proteostasis of master transcription factors in embryonic stem cells.
SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway.
1,25-Dihydroxyvitamin D deficiency induces sarcopenia by inducing skeletal muscle cell senescence.
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Dysregulation of tumour microenvironment driven by circ-TPGS2/miR-7/TRAF6/NF-κB axis facilitates breast cancer cell motility.
Circular RNA GLIS2 promotes colorectal cancer cell motility via activation of the NF-κB pathway.
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Zhang H, Liu Y, Zhang W, Guo Y, Lin A, Jin Y, Lu P, Fang Y, Zhang H, Qu L, Luo P, Wu L, Chen Y, Kang X, Wang L, Jiang A
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Journal of molecular histology 2026 Mar 26;57(2)
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Neonatal Spinal-Cord-Like Scaffold with Hierarchical Structural and Neurogenetic Microenvironments for Spinal Cord Injury Repair.
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ACS nano 2026 Feb 24;20(7):5423-5437
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SIRT5 induces glomerular sclerosis in diabetic nephropathy through p53.
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Lnc-DARVR/miR-365-1-5p/LAMB1 axis regulates rotavirus replication via the complement C3 pathway.
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LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment.
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E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair.
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Acta biomaterialia 2025 Mar 1;194:122-139
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Bushen Tongluo recipe improves oxidative stress homeostasis, inhibits transforming growth factor/Notch signaling pathway, and regulates the lncRNA maternally expressed gene 3/miR-145 axis to delay diabetic kidney disease.
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FOXK2 in skeletal muscle development: a new pathogenic gene for congenital myopathy with ptosis.
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Cold atmospheric plasma-activated saline alleviates secondary injury post-SCI by inhibiting extracellular matrix remodeling and infiltration of proinflammatory macrophages.
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Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury.
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Recombinant Humanized Collagen Enhances Secreted Protein Levels of Fibroblasts and Facilitates Rats' Skin Basement Membrane Reinforcement.
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Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.
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Frontiers in bioengineering and biotechnology 2024;12:1347995
Galectin-3 inhibition reduces fibrotic scarring and promotes functional recovery after spinal cord injury in mice.
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A proteomics-based study of the mechanism of oxymatrine to ameliorate hepatic fibrosis in mice.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2024 Oct 15;1247:124280
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
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Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
Wu J, Wang C, Sun S, Ren T, Pan L, Liu H, Hou S, Wu S, Yan X, Zhang J, Zhao X, Liu W, Zhu S, Wei S, Zhang C, Jia X, Zhang Q, Yu Z, Zhuo Y, Zhao Q, Yang C, Wang N
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Protein & cell 2024 Jul 20;15(8):594-611
Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear.
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iScience 2024 Jul 19;27(7):110331
iScience 2024 Jul 19;27(7):110331
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.
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Scientific reports 2024 Jan 28;14(1):2328
Scientific reports 2024 Jan 28;14(1):2328
Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.
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iScience 2024 Apr 19;27(4):109351
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
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Journal of virology 2023 May 31;97(5):e0171822
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells.
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EMBO reports 2023 Mar 6;24(3):e55683
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
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Scientific reports 2023 Jul 5;13(1):10906
Scientific reports 2023 Jul 5;13(1):10906
3D artificial sebocyte glands from inertial focusing effect for facile and flexible analysis of light damage and drug screening.
Tang T, Wei Y, Jia H, Wang L, Xu Y, Zhang P
Biotechnology journal 2023 Aug;18(8):e2200634
Biotechnology journal 2023 Aug;18(8):e2200634
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
Zhang B, Li X, Zhou X, Lou C, Wang S, Lv H, Zhang G, Fang Y, Yin D, Shang P
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iScience 2023 Aug 18;26(8):107365
miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway.
Xu L, Zhang Y, Long H, Zhou B, Jiang H
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Journal of ophthalmology 2022;2022:3584192
Cytosolic p53 Inhibits Parkin-Mediated Mitophagy and Promotes Acute Liver Injury Induced by Heat Stroke.
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Frontiers in immunology 2022;13:859231
Frontiers in immunology 2022;13:859231
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
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Inflammation and regeneration 2022 Sep 26;42(1):44
Inflammation and regeneration 2022 Sep 26;42(1):44
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4.
Song XY, Chen YY, Liu WT, Cong L, Zhang JL, Zhang Y, Zhang YY
International journal of molecular medicine 2022 Jun;49(6)
International journal of molecular medicine 2022 Jun;49(6)
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
Li Y, Yang L, Hu F, Xu J, Ye J, Liu S, Wang L, Zhuo M, Ran B, Zhang H, Ye J, Xiao J
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
ACS applied materials & interfaces 2022 Jun 8;14(22):25155-25172
Stub1 maintains proteostasis of master transcription factors in embryonic stem cells.
Mamun MMA, Khan MR, Zhu Y, Zhang Y, Zhou S, Xu R, Bukhari I, Thorne RF, Li J, Zhang XD, Liu G, Chen S, Wu M, Song X
Cell reports 2022 Jun 7;39(10):110919
Cell reports 2022 Jun 7;39(10):110919
SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway.
Li Z, Yu S, Liu Y, Hu X, Li Y, Xiao Z, Chen Y, Tian D, Xu X, Cheng L, Zheng M, Jing J
Journal of neuroinflammation 2022 Apr 16;19(1):95
Journal of neuroinflammation 2022 Apr 16;19(1):95
1,25-Dihydroxyvitamin D deficiency induces sarcopenia by inducing skeletal muscle cell senescence.
Yu S, Ren B, Chen H, Goltzman D, Yan J, Miao D
American journal of translational research 2021;13(11):12638-12649
American journal of translational research 2021;13(11):12638-12649
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
Yu Y, Liu X, Zhao Z, Xu Z, Qiao Y, Zhou Y, Qiao H, Zhong J, Dai J, Suo G
Frontiers in pharmacology 2021;12:747223
Frontiers in pharmacology 2021;12:747223
M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway.
Li Z, Zheng M, Yu S, Yao F, Luo Y, Liu Y, Tian D, Cheng L, Jing J
Frontiers in pharmacology 2021;12:670813
Frontiers in pharmacology 2021;12:670813
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Gao C, Xu Y, Liang Z, Wang Y, Shang Q, Zhang S, Wang C, Ni M, Wu D, Huang Z, Pang T
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Dysregulation of tumour microenvironment driven by circ-TPGS2/miR-7/TRAF6/NF-κB axis facilitates breast cancer cell motility.
Wang S, Feng X, Wang Y, Li Q, Li X
Autoimmunity 2021 Aug;54(5):284-293
Autoimmunity 2021 Aug;54(5):284-293
Circular RNA GLIS2 promotes colorectal cancer cell motility via activation of the NF-κB pathway.
Chen J, Yang X, Liu R, Wen C, Wang H, Huang L, Li W, Zhu Z, Zhu Y, Liu H
Cell death & disease 2020 Sep 23;11(9):788
Cell death & disease 2020 Sep 23;11(9):788
IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.
Zhang W, Lu Y, Li X, Zhang J, Lin W, Zhang W, Zheng L, Li X
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):296
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway.
Huang J, Chen S, Cai D, Bian D, Wang F
Life sciences 2018 Jun 15;203:48-53
Life sciences 2018 Jun 15;203:48-53
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Sun JX, Chang TF, Li MH, Sun LJ, Yan XC, Yang ZY, Liu Y, Xu WQ, Lv Y, Su JB, Liang L, Han H, Dou GR, Wang YS
Angiogenesis 2018 Aug;21(3):635-652
Angiogenesis 2018 Aug;21(3):635-652
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
Hu YH, Chen Q, Lu YX, Zhang JM, Lin C, Zhang F, Zhang WJ, Li XM, Zhang W, Li XN
Oncotarget 2017 Jul 11;8(28):46191-46203
Oncotarget 2017 Jul 11;8(28):46191-46203
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