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- Antibody Data
- Antigen structure
- References [24]
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- Validations
- Immunocytochemistry [2]
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- Product number
- ADI-VAM-PS003-D - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-VAM-PS003-D, RRID:AB_2038857
- Product name
- Bassoon, mAb (SAP7F407)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- Protein G affinity purified. Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
- Isotype
- IgG
- Antibody clone number
- SAP7F407
Submitted references Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury.
GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons.
TIMP-1 affects the spatial distribution of dendritic processes of second-order neurons in a rat model of Retinitis Pigmentosa.
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
The phospholipid-binding protein SESTD1 negatively regulates dendritic spine density by interfering with Rac1-Trio8 signaling pathway.
Mechanisms of splicing-dependent trans-synaptic adhesion by PTPδ-IL1RAPL1/IL-1RAcP for synaptic differentiation.
LKB1 and AMPK regulate synaptic remodeling in old age.
Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis.
ArfGAP3 is a component of the photoreceptor synaptic ribbon complex and forms an NAD(H)-regulated, redox-sensitive complex with RIBEYE that is important for endocytosis.
N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons.
Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain.
Protein composition of immunoprecipitated synaptic ribbons.
Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.
Polarized targeting of neurexins to synapses is regulated by their C-terminal sequences.
Mechanisms of prolonged presynaptic Ca2+ signaling and glutamate release induced by TRPV1 activation in rat sensory neurons.
gamma-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina.
Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice.
Neuronal differentiation and synaptogenesis in retinoblastoma.
Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord.
Ultrastructural localization of active zone and synaptic vesicle proteins in a preassembled multi-vesicle transport aggregate.
Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory.
Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP.
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.
The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution.
Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, Nakamura M, Okano H
Stem cell reports 2016 Jan 12;6(1):1-8
Stem cell reports 2016 Jan 12;6(1):1-8
GSK3β inhibition promotes synaptogenesis in Drosophila and mammalian neurons.
Cuesto G, Jordán-Álvarez S, Enriquez-Barreto L, Ferrús A, Morales M, Acebes Á
PloS one 2015;10(3):e0118475
PloS one 2015;10(3):e0118475
TIMP-1 affects the spatial distribution of dendritic processes of second-order neurons in a rat model of Retinitis Pigmentosa.
Shin JA, Eom YS, Yu WQ, Grzywacz NM, Craft CM, Lee EJ
Experimental eye research 2015 Nov;140:41-52
Experimental eye research 2015 Nov;140:41-52
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gómez-Galán M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T
Nature neuroscience 2015 Jun;18(6):826-35
Nature neuroscience 2015 Jun;18(6):826-35
The phospholipid-binding protein SESTD1 negatively regulates dendritic spine density by interfering with Rac1-Trio8 signaling pathway.
Lee CC, Huang CC, Hsu KS
Scientific reports 2015 Aug 14;5:13250
Scientific reports 2015 Aug 14;5:13250
Mechanisms of splicing-dependent trans-synaptic adhesion by PTPδ-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Yamagata A, Yoshida T, Sato Y, Goto-Ito S, Uemura T, Maeda A, Shiroshima T, Iwasawa-Okamoto S, Mori H, Mishina M, Fukai S
Nature communications 2015 Apr 24;6:6926
Nature communications 2015 Apr 24;6:6926
LKB1 and AMPK regulate synaptic remodeling in old age.
Samuel MA, Voinescu PE, Lilley BN, de Cabo R, Foretz M, Viollet B, Pawlyk B, Sandberg MA, Vavvas DG, Sanes JR
Nature neuroscience 2014 Sep;17(9):1190-7
Nature neuroscience 2014 Sep;17(9):1190-7
Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis.
Moscato EH, Peng X, Jain A, Parsons TD, Dalmau J, Balice-Gordon RJ
Annals of neurology 2014 Jul;76(1):108-19
Annals of neurology 2014 Jul;76(1):108-19
ArfGAP3 is a component of the photoreceptor synaptic ribbon complex and forms an NAD(H)-regulated, redox-sensitive complex with RIBEYE that is important for endocytosis.
Dembla M, Wahl S, Katiyar R, Schmitz F
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5245-60
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Apr 9;34(15):5245-60
N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons.
Yam PT, Pincus Z, Gupta GD, Bashkurov M, Charron F, Pelletier L, Colman DR
PloS one 2013;8(11):e79679
PloS one 2013;8(11):e79679
Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain.
Mandemakers W, Abuhatzira L, Xu H, Caromile LA, Hébert SS, Snellinx A, Morais VA, Matta S, Cai T, Notkins AL, De Strooper B
Diabetologia 2013 Jul;56(7):1547-56
Diabetologia 2013 Jul;56(7):1547-56
Protein composition of immunoprecipitated synaptic ribbons.
Kantardzhieva A, Peppi M, Lane WS, Sewell WF
Journal of proteome research 2012 Feb 3;11(2):1163-74
Journal of proteome research 2012 Feb 3;11(2):1163-74
Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.
Chen J, Billings SE, Nishimune H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jan 12;31(2):512-25
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Jan 12;31(2):512-25
Polarized targeting of neurexins to synapses is regulated by their C-terminal sequences.
Fairless R, Masius H, Rohlmann A, Heupel K, Ahmad M, Reissner C, Dresbach T, Missler M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Nov 26;28(48):12969-81
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Nov 26;28(48):12969-81
Mechanisms of prolonged presynaptic Ca2+ signaling and glutamate release induced by TRPV1 activation in rat sensory neurons.
Medvedeva YV, Kim MS, Usachev YM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 May 14;28(20):5295-311
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 May 14;28(20):5295-311
gamma-Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina.
Lefebvre JL, Zhang Y, Meister M, Wang X, Sanes JR
Development (Cambridge, England) 2008 Dec;135(24):4141-51
Development (Cambridge, England) 2008 Dec;135(24):4141-51
Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice.
Bartsch U, Oriyakhel W, Kenna PF, Linke S, Richard G, Petrowitz B, Humphries P, Farrar GJ, Ader M
Experimental eye research 2008 Apr;86(4):691-700
Experimental eye research 2008 Apr;86(4):691-700
Neuronal differentiation and synaptogenesis in retinoblastoma.
Johnson DA, Zhang J, Frase S, Wilson M, Rodriguez-Galindo C, Dyer MA
Cancer research 2007 Mar 15;67(6):2701-11
Cancer research 2007 Mar 15;67(6):2701-11
Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord.
Yan J, Xu L, Welsh AM, Hatfield G, Hazel T, Johe K, Koliatsos VE
PLoS medicine 2007 Feb;4(2):e39
PLoS medicine 2007 Feb;4(2):e39
Ultrastructural localization of active zone and synaptic vesicle proteins in a preassembled multi-vesicle transport aggregate.
Tao-Cheng JH
Neuroscience 2007 Dec 12;150(3):575-84
Neuroscience 2007 Dec 12;150(3):575-84
Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory.
Lee HK, Takamiya K, Han JS, Man H, Kim CH, Rumbaugh G, Yu S, Ding L, He C, Petralia RS, Wenthold RJ, Gallagher M, Huganir RL
Cell 2003 Mar 7;112(5):631-43
Cell 2003 Mar 7;112(5):631-43
Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP.
Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM
Neuron 2003 Feb 20;37(4):625-38
Neuron 2003 Feb 20;37(4):625-38
Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.
Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y
The Journal of cell biology 2002 Aug 5;158(3):577-90
The Journal of cell biology 2002 Aug 5;158(3):577-90
The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution.
Phillips GR, Huang JK, Wang Y, Tanaka H, Shapiro L, Zhang W, Shan WS, Arndt K, Frank M, Gordon RE, Gawinowicz MA, Zhao Y, Colman DR
Neuron 2001 Oct 11;32(1):63-77
Neuron 2001 Oct 11;32(1):63-77
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of Bassoon: Lane 1: MW marker, Lane 2: Rat Brain Tissue Lysate.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of bassoon localization in the rat brain cerebellar molecular layer using Bassoon, mAb (SAP7F407).
