ABIN252469

antibody from antibodies-online

Targeting: TNFRSF11B OCIF, OPG, TR1

Provider product page for ABIN252469

Western blot

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [26]
Comments [0]
Validations
Western blot [2]
Immunohistochemistry [4]
Flow cytometry [1]

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Product number: ABIN252469 - Provider product page
Provider: antibodies-online
Product name: anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 20-37) antibody
Antibody type: Monoclonal
Description: Protein G purified
Reactivity: Human, Rat
Host: Mouse
Epitope: AA 20-37
Isotype: IgG
Antibody clone number: 98A1071
Vial size: 0.1 mg
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Handling: Avoid freeze-thaw cycles

TNFRSF11B protein structure - ABIN252469 shown in red.

Submitted references Impairment of PTX3 expression in osteoblasts: a key element for osteoporosis.

Scimeca M, Salustri A, Bonanno E, Nardozi D, Rao C, Piccirilli E, Feola M, Tancredi V, Rinaldi A, Iolascon G, Orlandi A, Gasbarra E, Maffulli N, Brandi ML, Tarantino U
Cell death & disease 2017 Oct 12;8(10):e3125

Influence of receptor activator of nuclear factor kappa B ligand, osteoprotegerin and interleukin-33 on bone metabolism in patients with long-standing ulcerative colitis.

Stanisławowski M, Wiśniewski P, Guzek M, Wierzbicki PM, Adrych K, Smoczyński M, Sworczak K, Celiński K, Kmieć Z
Journal of Crohn's & colitis 2014 Aug;8(8):802-10

Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases.

Larson SR, Zhang X, Dumpit R, Coleman I, Lakely B, Roudier M, Higano CS, True LD, Lange PH, Montgomery B, Corey E, Nelson PS, Vessella RL, Morrissey C
The Prostate 2013 Jun;73(9):932-40

Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis.

Boumans MJ, Thurlings RM, Yeo L, Scheel-Toellner D, Vos K, Gerlag DM, Tak PP
Annals of the rheumatic diseases 2012 Jan;71(1):108-13

Expression of osteoprotegerin in human fat tissue; implications for chronic kidney disease.

Witasp A, Carrero JJ, Hammarqvist F, Qureshi AR, Heimbürger O, Schalling M, Lindholm B, Nordfors L, Stenvinkel P
European journal of clinical investigation 2011 May;41(5):498-506

Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis.

Tomlins C, Storey A
Carcinogenesis 2010 Dec;31(12):2155-64

Noncollagenous bone matrix proteins as a part of calcific aortic valve disease regulation.

Pohjolainen V, Taskinen P, Soini Y, Rysä J, Ilves M, Juvonen T, Ruskoaho H, Leskinen H, Satta J
Human pathology 2008 Nov;39(11):1695-701

The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation.

Vandooren B, Cantaert T, Noordenbos T, Tak PP, Baeten D
Arthritis and rheumatism 2008 Mar;58(3):718-29

The antibody MAB8051 directed against osteoprotegerin detects carbonic anhydrase II: implications for association studies with human cancers.

Waterman EA, Cross NA, Lippitt JM, Cross SS, Rehman I, Holen I, Hamdy FC, Eaton CL
International journal of cancer 2007 Nov 1;121(9):1958-66

RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis.

Pettit AR, Walsh NC, Manning C, Goldring SR, Gravallese EM
Rheumatology (Oxford, England) 2006 Sep;45(9):1068-76

Osteoprotegerin (OPG) binds with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): suppression of TRAIL-induced apoptosis in ameloblastomas.

Sandra F, Hendarmin L, Nakamura S
Oral oncology 2006 Apr;42(4):415-20

Hepatic osteodystrophy: does the osteoprotegerin/receptor activator of nuclear factor-kB ligand system play a role?

Gaudio A, Lasco A, Morabito N, Atteritano M, Vergara C, Catalano A, Fries W, Trifiletti A, Frisina N
Journal of endocrinological investigation 2005 Sep;28(8):677-82

Osteoprotegerin is expressed in colon carcinoma cells.

Pettersen I, Bakkelund W, Smedsrød B, Sveinbjørnsson B
Anticancer research 2005 Nov-Dec;25(6B):3809-16

Association of osteoprotegerin with human abdominal aortic aneurysm progression.

Moran CS, McCann M, Karan M, Norman P, Ketheesan N, Golledge J
Circulation 2005 Jun 14;111(23):3119-25

Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone.

Sandra F, Hendarmin L, Kukita T, Nakao Y, Nakamura N, Nakamura S
Oral oncology 2005 Jul;41(6):637-44

The RANKL/OPG system and bone mineral density in patients with chronic liver disease.

Moschen AR, Kaser A, Stadlmann S, Millonig G, Kaser S, Mühllechner P, Habior A, Graziadei I, Vogel W, Tilg H
Journal of hepatology 2005 Dec;43(6):973-83

The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss.

Moschen AR, Kaser A, Enrich B, Ludwiczek O, Gabriel M, Obrist P, Wolf AM, Tilg H
Gut 2005 Apr;54(4):479-87

Osteoprotegerin production by human intestinal epithelial cells: a potential regulator of mucosal immune responses.

Vidal K, Serrant P, Schlosser B, van den Broek P, Lorget F, Donnet-Hughes A
American journal of physiology. Gastrointestinal and liver physiology 2004 Oct;287(4):G836-44

Osteoprotegerin in human milk: a potential role in the regulation of bone metabolism and immune development.

Vidal K, van den Broek P, Lorget F, Donnet-Hughes A
Pediatric research 2004 Jun;55(6):1001-8

Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis.

Golledge J, McCann M, Mangan S, Lam A, Karan M
Stroke 2004 Jul;35(7):1636-41

Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells.

Standal T, Seidel C, Hjertner Ø, Plesner T, Sanderson RD, Waage A, Borset M, Sundan A
Blood 2002 Oct 15;100(8):3002-7

Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression.

Pearse RN, Sordillo EM, Yaccoby S, Wong BR, Liau DF, Colman N, Michaeli J, Epstein J, Choi Y
Proceedings of the National Academy of Sciences of the United States of America 2001 Sep 25;98(20):11581-6

Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.

Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater AM, Cabanillas F, Aggarwal BB, Younes A
Blood 2001 Nov 1;98(9):2784-90

17beta-estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-alpha.

Saika M, Inoue D, Kido S, Matsumoto T
Endocrinology 2001 Jun;142(6):2205-12

The osteoprotegerin/receptor activator of nuclear factor kappaB/receptor activator of nuclear factor kappaB ligand system in cartilage.

Komuro H, Olee T, Kühn K, Quach J, Brinson DC, Shikhman A, Valbracht J, Creighton-Achermann L, Lotz M
Arthritis and rheumatism 2001 Dec;44(12):2768-76

Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression.

Kobayashi Y, Hashimoto F, Miyamoto H, Kanaoka K, Miyazaki-Kawashita Y, Nakashima T, Shibata M, Kobayashi K, Kato Y, Sakai H
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000 Oct;15(10):1924-34

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