AB10089-200

antibody from SICGEN
Targeting: ATXN3 ATX3, JOS, MJD, SCA3
Provider product page for AB10089-200

Antibody data

Product number
AB10089-200 - Provider product page
Provider
SICGEN
Product name
Anti-ATXN3
Antibody type
Polyclonal
Description
Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
Reactivity
Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other
Host
Goat
Conjugate
Unconjugated
Isotype
IgG
Vial size
600 µg
Concentration
3 mg/ml
Storage
Store at -20 C for long-term storage.
Handling
The antibody solution should be gently mixed before use.
ATXN3 protein structure - AB10089-200 shown in red.