CABT-B9214

antibody from Creative Diagnostics

Targeting: GPLD1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B9214

Provider

Creative Diagnostics

Product name

Mouse anti-Human GPI-Phospholipase D monoclonal antibody, clone 26/HQJ

Antibody type

Monoclonal

Description

Glycosylphosphatidylinositol (GPI)-anchored proteins are involved in the regulation of numerous cell-surface activities including the complement cascade, activation of plasminogen, T-cell activation, cell-to-cell adhesion, and macromolecule transport through the membrane. GPI-containing proteins are very abundant at the caveolae. GPI-specific phospholipase D (GPI-PLD) hydrolyzes the covalently bound GPI moiety which functions as an anchor for many cell-surface proteins. Present at high levels in the plasma, GPI-PLD is also secreted by some cell types in culture. This protein releases the GPI-anchored, complement regulatory protein decay accelerating factor (DAF) from HeLa cells, as well as the basic fibroblast growth factor (bFGF)-bound heparin sulfate proteoglycan from bone marrow stromal cells. GPI-PLD contains Ca2+ and Zn2+ binding sites and bears some further structural and perhaps functional similarities to the integrins.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

26/HQJ

Vial size

50 _g

Concentration

250 Ã×g/ml

Storage

Store undiluted at -20°C.