11178-1-AP
antibody from Proteintech Group
Targeting: EXOSC10
p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p
Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11178-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11178-1-AP, RRID:AB_2293792
- Product name
- EXOSC10 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EXOSC10 antibody (Cat. #11178-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cytoplasmic DIS3 is an exosome-independent endoribonuclease with catalytic activity toward circular RNAs.
LncRNA EP300-AS1 interacts with PTBP1 to destabilize PRMT5 mRNA and suppresses NSCLC growth and metastasis.
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response.
NAT10 Drives Cisplatin Chemoresistance by Enhancing ac4C-Associated DNA Repair in Bladder Cancer.
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.
Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling.
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
Human Telomerase RNA Processing and Quality Control.
Latini C, Eichlinger J, Fuchs AL, Zhai SN, Ho-Xuan H, Lehmann G, Glažar P, Rajewsky N, Bruckmann A, Yang L, Sprangers R, Meister G
Cell reports 2025 Jun 24;44(6):115769
Cell reports 2025 Jun 24;44(6):115769
LncRNA EP300-AS1 interacts with PTBP1 to destabilize PRMT5 mRNA and suppresses NSCLC growth and metastasis.
Chen J, Fan C, Song S, Zhang D
Cell death & disease 2025 Aug 11;16(1):607
Cell death & disease 2025 Aug 11;16(1):607
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response.
Wofford W, Kim J, Kim D, Janneh AH, Lee HG, Atilgan FC, Oleinik N, Kassir MF, Saatci O, Chakraborty P, Tokat UM, Gencer S, Howley B, Howe P, Mehrotra S, Sahin O, Ogretmen B
Cell reports 2024 Aug 27;43(8):114532
Cell reports 2024 Aug 27;43(8):114532
NAT10 Drives Cisplatin Chemoresistance by Enhancing ac4C-Associated DNA Repair in Bladder Cancer.
Xie R, Cheng L, Huang M, Huang L, Chen Z, Zhang Q, Li H, Lu J, Wang H, Zhou Q, Huang J, Chen X, Lin T
Cancer research 2023 May 15;83(10):1666-1683
Cancer research 2023 May 15;83(10):1666-1683
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JN, Dos Santos Souza C, Zhang S, Castelli L, Hautbergue G, Azzouz M, Gordon D, Krogan N, Ferraiuolo L, Snyder MP, Shaw PJ, Rehwinkel J, Cooper-Knock J
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.
Matkovic R, Morel M, Lanciano S, Larrous P, Martin B, Bejjani F, Vauthier V, Hansen MMK, Emiliani S, Cristofari G, Gallois-Montbrun S, Margottin-Goguet F
Nature communications 2022 Jan 10;13(1):66
Nature communications 2022 Jan 10;13(1):66
Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling.
Ulmke PA, Xie Y, Sokpor G, Pham L, Shomroni O, Berulava T, Rosenbusch J, Basu U, Fischer A, Nguyen HP, Staiger JF, Tuoc T
Development (Cambridge, England) 2021 Feb 8;148(3)
Development (Cambridge, England) 2021 Feb 8;148(3)
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.
Jiao AL, Perales R, Umbreit NT, Haswell JR, Piper ME, Adams BD, Pellman D, Kennedy S, Slack FJ
RNA (New York, N.Y.) 2019 Mar;25(3):352-363
RNA (New York, N.Y.) 2019 Mar;25(3):352-363
Human Telomerase RNA Processing and Quality Control.
Tseng CK, Wang HF, Burns AM, Schroeder MR, Gaspari M, Baumann P
Cell reports 2015 Dec 15;13(10):2232-43
Cell reports 2015 Dec 15;13(10):2232-43
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The EXOSC10 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EXOSC10. This antibody recognizes human, mouse, rat antigen. The EXOSC10 antibody has been validated for the following applications: ELISA, IHC analysis.