Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA004829 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA004829, RRID:AB_1079495
- Product name
- Anti-NNT
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human NNT, Gene description: nicotinamide nucleotide transhydrogenase, Validated applications: WB, IHC, Uniprot ID: Q13423, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Longitudinal in vivo metabolic labeling reveals tissue-specific mitochondrial proteome turnover rates and proteins selectively altered by parkin deficiency
Mylk3null C57BL/6N mice develop cardiomyopathy, whereasNntnull C57BL/6J mice do not
Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice
Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma
Stauch K, Totusek S, Trease A, Estrella L, Emanuel K, Fangmeier A, Fox H
Scientific Reports 2023;13(1)
Scientific Reports 2023;13(1)
Mylk3null C57BL/6N mice develop cardiomyopathy, whereasNntnull C57BL/6J mice do not
Williams J, Paudyal A, Awad S, Nicholson J, Grzesik D, Botta J, Meimaridou E, Maharaj A, Stewart M, Tinker A, Cox R, Metherell L
Life Science Alliance 2020;3(4):e201900593
Life Science Alliance 2020;3(4):e201900593
Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons
Gal J, Chen J, Katsumata Y, Fardo D, Wang W, Artiushin S, Price D, Anderson S, Patel E, Zhu H, Nelson P
Journal of Neuropathology & Experimental Neurology 2018;77(1):21-39
Journal of Neuropathology & Experimental Neurology 2018;77(1):21-39
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice
Meimaridou E, Goldsworthy M, Chortis V, Fragouli E, Foster P, Arlt W, Cox R, Metherell L
Journal of Endocrinology 2018;236(1):13-28
Journal of Endocrinology 2018;236(1):13-28
Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma
Chortis V, Taylor A, Doig C, Walsh M, Meimaridou E, Jenkinson C, Rodriguez-Blanco G, Ronchi C, Jafri A, Metherell L, Hebenstreit D, Dunn W, Arlt W, Foster P
Endocrinology 2018;159(8):2836-2849
Endocrinology 2018;159(8):2836-2849
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human heart muscle and skin tissues using HPA004829 antibody. Corresponding NNT RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol