CABT-L687

antibody from Creative Diagnostics
Targeting: ITGAL CD11A, LFA-1
Provider product page for CABT-L687
No application information provided.

Antibody data

Product number
CABT-L687 - Provider product page
Provider
Creative Diagnostics
Product name
Rabbit Anti-Human ITGAL monoclonal antibody, clone TD67-12
Antibody type
Monoclonal
Description
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors
ITGAL protein structure - CABT-L687 shown in red.