Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AFC-TAB-024 - Provider product page
- Provider
- Creative Biolabs
- Product name
- Afuco? Anti-ITGAL ADCC Recombinant Antibody (Efalizumab), ADCC Enhanced
- Antibody type
- Monoclonal
- Description
- This product is an ADCC enhanced antibody produced by our Afuco? platform. Recombinant monoclonal antibody to Human CD11A. Efalizumab (trade name Raptiva, Genentech, Merck Serono) is a formerly available medication designed to treat autoimmune diseases, originally marketed to treat psoriasis. As implied by the suffix -zumab, it is a recombinant humanized monoclonal antibody administered once weekly by subcutaneous injection. Efalizumab binds to the CD11a subunit of lymphocyte function-associated antigen 1 and acts as an immunosuppressant by inhibiting lymphocyte activation and cell migration out of blood vessels into tissues. Efalizumab was associated with fatal brain infections and was withdrawn from the market in 2009.
- Reactivity
- Human
- Host
- Human
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- Efalizumab
- Storage
- Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.
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