Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-1021-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-DEPTOR/DEPDC6 Antibody
- Antibody type
- Polyclonal
- Description
- DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant DEPTOR
protein (amino acids 111-301) was
used as the immunogen for this anti
body.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
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- Experimental details
- Western blot analysis DEPTOR. Anti-DEPTOR antibody (11-1021) was used at 2 µg/ml on HepG2 lysate.