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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16898-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16898-1-AP, RRID:AB_2295304
- Product name
- HMGCL antibody
- Antibody type
- Polyclonal
- Description
- HMGCL antibody (Cat. #16898-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphorylation by IKKβ Promotes the Degradation of HMGCL via NEDD4 in Lung Cancer.
Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine.
Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria.
Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation.
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.
Zhong C, Xiong G, Yang H, Du X, Du J, Yao F, Fang W, Deng Y
International journal of biological sciences 2023;19(4):1110-1122
International journal of biological sciences 2023;19(4):1110-1122
Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine.
Cortez NE, Lanzi CR, Vahmani P, Matsukuma K, Mackenzie GG
Oncology letters 2023 Nov;26(5):479
Oncology letters 2023 Nov;26(5):479
Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria.
Speck SL, Bhatt DP, Zhang Q, Adak S, Yin L, Dong G, Feng C, Zhang W, Ben Major M, Wei X, Semenkovich CF
Cell reports 2023 Nov 28;42(11):113389
Cell reports 2023 Nov 28;42(11):113389
Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation.
Goldberg EL, Letian A, Dlugos T, Leveau C, Dixit VD
The Journal of biological chemistry 2023 Mar;299(3):103005
The Journal of biological chemistry 2023 Mar;299(3):103005
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
Cui X, Yun X, Sun M, Li R, Lyu X, Lao Y, Qin X, Yu W
Hepatology international 2023 Apr;17(2):377-392
Hepatology international 2023 Apr;17(2):377-392
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
Li JT, Yin M, Wang D, Wang J, Lei MZ, Zhang Y, Liu Y, Zhang L, Zou SW, Hu LP, Zhang ZG, Wang YP, Wen WY, Lu HJ, Chen ZJ, Su D, Lei QY
Nature cell biology 2020 Feb;22(2):167-174
Nature cell biology 2020 Feb;22(2):167-174
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.
Huang D, Li T, Wang L, Zhang L, Yan R, Li K, Xing S, Wu G, Hu L, Jia W, Lin SC, Dang CV, Song L, Gao P, Zhang H
Cell research 2016 Oct;26(10):1112-1130
Cell research 2016 Oct;26(10):1112-1130
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 16898-1-AP(HMGCL antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16898-1-AP(HMGCL antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HMGCL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HMGCL. This antibody recognizes human, mouse, rat antigen. The HMGCL antibody has been validated for the following applications: ELISA, WB, IHC analysis.
